What is Peractin, a drug now only available by prescription?

2024-07-02 04:45:00

Ozempic was in the news a few weeks ago for its weight loss benefits; it’s now giving way to Peractin. From July 10th, Peractin will no longer be available for free. To get it, you must give a prescription to a pharmacist. This antihistamine cyproheptadine, sold as Peractin by Teofarma Laboratories, is indicated for the treatment of allergy symptoms such as allergic rhinitis, conjunctivitis or urticaria in adults and children over 6 years of age.

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But the drug also has orexigenic effects, meaning it can increase the user’s appetite. This trend appears on social networks of some influencers, who take the drug in order to quickly increase the size of their buttocks. Poupette Kenza highlighted some of the effects of this drug on the social network TikTok. “In less than a month, you have gained at least three kilograms. […] The goal is to create a defined waistline that creates the illusion of an hourglass silhouette. » In the end, the young woman retracted her remarks and assured that she was unaware of the risks of taking the drug.

Drowsiness, constipation, and vision problems

In fact, this kind of abuse is not without health risks, as the National Agency for the Safety of Medicines and Healthcare products (ANSM) points out: “Cyproheptadine also has a variety of adverse effects, including central effects (reduced alertness, drowsiness) and anti-inflammatory effects. Cholinergic drugs (constipation, visual disturbances, palpitations, etc.), which may be important in this case of abuse » Back in January 2022. ANSM warns about diversion of this drug : “The off-label use of cyproheptadine as an orexigenic agent to induce weight gain for cosmetic purposes has been reported to be potentially dangerous. It has been particularly prominent on social networks. »

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Therefore, after issuing the warning, the Food and Drug Administration chose to crack down by immediately restricting the use of the drug: “We have therefore decided to include cyproheptadine in the list of toxic substances 1. From July 10, 2024, any product containing cyproheptadine will All drugs must be dispensed with a doctor’s prescription. » Asked by AFP, the agency’s medical director Isabelle Yoldjian said the decision was “based on what we saw on social media. The use of cosmetics is always vigorously promoted on the Internet.”

ANSM also reminds health care professionals that “when prescribing and dispensing medications, patients must be informed of the risks associated with their use and the rules for their correct use (observance of dosage, duration of treatment, route of administration, etc.)”.

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