2023-09-22 17:07:37
An English study published in the journal Microbiology takes a very old remedy out of the closet and notes that it effectively treats, and without antibiotics, bacterial infections located in wounds and burns.
Antibiotic resistance represents a major challenge for modern medicine. Over the decades, their widespread and sometimes inappropriate use has led to the emergence of bacteria resistant to these drugs. This “antibiotic resistance” makes the treatment of infections increasingly difficult, and increases the risk of serious or even fatal complications. This is why research is increasingly looking at other solutions that do not involve antibiotics in order to treat bacterial infections, particularly in wounds and burns.
Honey and vinegar, excellent antibacterials
Among other solutions, acetic acid, an excellent antibacterial contained in vinegar, has proven itself in various scientific studies, but also in practice, particularly in many hospitals in the United Kingdom. A British national survey of burns treatment units, carried out in October 2019, revealed that approximately a third of units used dressings soaked in acetic acid (2.5 to 3%) to treat burns infected with Pseudomonas aeruginosa.
One of the other ancient remedies, which is experiencing a comeback for infected wounds, is medicinal grade honey. However, both honey and vinegar, used alone, do not seem effective enough to tackle biofilms which protect certain bacterial colonies, including on wounds, by making them resistant to treatments. It is to overcome this biofilm problem that a team of researchers from the University of Warwick (1) (United Kingdom) looked into the benefits of a combined use of medicinal grade honey and food vinegar to clean wounds.
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Oxymel to kill bacteria
After testing different combinations and proportions of honey, vinegar and acetic acid in vitro, the researchers were able to observe that oxymel with medicinal honey and whole food vinegar might overcome the biofilm barrier and cause many more bacteria to die. The research team found that the red wine vinegar was particularly effective in synergy with honey once morest staphylococcus aureus (Staphylococcus aureus) while the pomegranate vinegar was able to fight bacteria Staphylococcus aureus et Pseudomona aeruginosa (pyocyanic bacillus).
English researchers are well aware of this, they did not invent lukewarm water. Indeed, the mixture of honey and vinegar, known asoxymel, has been used since ancient Rome “to wash or dress wounds and swellings”(2). However, with the advent of modern medicine and antibiotics, oxymel and many old-fashioned remedies have disappeared from medical practice. However, as the case of oxymel shows, they can remain as relevant as they are effective in dealing with diseases.
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Medicine of yesterday, medicine of tomorrow
These results are part of multidisciplinary research initiated in 2021 by Drs Erin Connelly and Freya Harrison from the University of Warwick. The first, specialized in the research of innovative molecules once morest antibiotic-resistant infections, joined forces with the second, which explores number of medieval and ancient medical treatises to identify ingredients and their logic of association. Together, they test the antimicrobial effectiveness of these ingredients and remedies with the tools of modern medicine (3). An exciting prospect as research in the field of antibiotic therapy has slowed down and that, too often in medicine, the race for innovation makes us forget thousands of years of accumulated knowledge and know-how.
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