What are the risk factors for recurrence?

2024-07-16 14:01:30

Source: National Cancer Institute – https://my.clevelandclinic.org/

When breast cancer returns months or even years following treatment has ended, it is called a recurrence. But this “relapse” may be:

Local : The cancer reappears in the same area as the original tumor;
regional : The cancer reappears near the original tumor, such as in the axillary lymph nodes;
from a distance : Breast cancer spreads from the original tumor to the lungs, bones, brain, or other parts of the body. This is metastatic breast cancer, often called stage 4 breast cancer, and actress Shannen Doherty has it. This is the most difficult form to treat because breast cancer can occur in multiple parts of the body.

according to’American Cancer Societyinflammatory breast cancer, and triple-negative breast cancer have the highest risk of recurrence.

What are the causes of breast cancer recurrence?

Breast cancer can come back when treatment fails to kill all the cancer cells, according to the Cleveland Clinic. These treatments for breast cancer are effective, but ” They can shrink breast cancer tumors to the point where tests no longer detect weakened cancer cells. (Also) Surgery to remove tumors is not always 100% effective. Before surgery, cancer cells may spread from the breast to nearby lymph nodes, tissue, or blood. »

What are the risk factors for recurrence?

The risk of recurrence depends on the prognostic factors of breast cancer. These risk factors play a decisive role in the choice of treatment. Depending on their presence, doctors choose this or that treatment. We specifically cite:

Patient’s age. « Breast cancers affecting younger women tend to be more aggressive, high-grade and advanced at diagnosis, with an increased risk of recurrence », the National Cancer Institute states;

tumor size. The prognosis is better when the tumor is smaller;

If breast cancer has spread In the lymph nodes, the risk of recurrence is greater;

Breast cancer grading. The Elston-Ellis tissue prognostic grading is classified from I to III and is based primarily on the appearance of the cancer cells (tumor architecture) and the rate at which they grow (mitotic activity);

Presence of signs of inflammation Local (redness, heat, etc.);

overweight and obesity

ETC.

pay attention : Most breast cancer recurrences occur within 5 years of treatment. But it’s not systemic, and in most cases the cancer never comes back.

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