45-time Red Devil Benteke hit twice with the head and once with a slider at the far post. Carles Gil scored for the visitors with a wonderful curl.
New England Revolution played much of the match with a man down following Giacomo Vrioni was sent off in the 25th minute.
Hugo Cuypers celebrated his debut for Chicago Fire on Saturday in the away match at Philadelphia Union. It became 2-2. Cuypers had no foot in the goals and was taken off two minutes before the end.
The striker transferred from AA Gent earlier this month for around twelve million euros.
Brecht Dejaegere was a starter for Charlotte, which opened the season with a 1-0 win once morest New York City. The midfielder was taken off following 78 minutes.
The season of Dante Vanzeir with the New York Red Bulls only starts on Sunday (at 11 p.m. Belgian time). Vanzeir and co move to Nashville.