Dr. Anan pointed out that Variola virus is very different from monkeypox, making the concern that monkeypox will mutate into human smallpox is almost impossible. Confirming that the smallpox vaccine is effective
25 May 2022 – Dr. Anan Chongkaewwatana, virologist Director of Animal Health and Management Innovation Research Group National Center for Genetic Engineering and Biotechnology (Biotech), National Science and Technology Development Agency (NSTDA) posted a message on Facebook. about monkey pox that
This phylogenetic tree shows the genetic affinity of the virus. orthopox virus In which there is monkey pox (MPXV) included, it can be seen that MPXV is divided into 2 groups, namely the WA (West Africa) clade and the CB (Congo Basin or Central Africa) clade. There is no difference between these 2 clades. much, but their ability to cause disease is different. The strain in question is WA, which is a mild strain. The mortality rate is much lower than CB.
The diagram also shows that Variola virus is very different from monkeypox, raising the concern that monkeypox will mutate into human smallpox almost impossible along the virus’ evolutionary path. What is interesting in this picture is The virus we use to develop as a vaccine against smallpox or human smallpox is Vaccinia virus, which is in the middle between monkeypox and human smallpox. When analyzing this diagram carefully, it can be seen that the Vaccinia virus is evolutionarily or genetically similar to that of monkeypox. more than smallpox
If vaccines from Vaccinia virus used for vaccination It can be used to protect people from smallpox as well. Until the virus can disappear naturally and the vaccine is closer to monkeypox than smallpox humans. There was no reason to worry that If monkey pox is causing a widespread epidemic, then this vaccine won’t work. Older technology that doesn’t need to upgrade anything.