Vicious circle: alcohol addiction would make you more sensitive to pain

2023-04-26 12:27:37

Alcohol dependence transforms the way the brain processes pain signals, leading to greater sensitivity to suffering in heavy drinkers, according to a new study.

“Pain is both a common symptom in patients with alcohol dependence, as well as a reason why people are driven to drink once more,” said lead author Marisa Roberto of the Institute. of Scripps Research by release, reported The Independant Monday.

The study, recently published in the British Journal of Pharmacologywould thus have demonstrated that certain biological mechanisms would be altered by alcohol dependence, changing the way pain is perceived.

Alcohol addiction affects nearly 30 million people in the United States alone, according to British media, and can lead to the development of many chronic diseases, such as heart disease, stroke, liver disease and certain cancers.

Thus, in more than half of the cases, the long-term consumption of alcoholic beverages would cause a form of persistent pain.

Addiction might also lead to allodynia, which is a feeling of pain triggered by harmless and normally nonpainful stimuli.

Through this study, scientists hope to be able to develop new drugs to treat chronic pain and hypersensitivity related to alcohol abuse.

To do this, they compared the data of three groups of adult rodents, one of which had heavy contact with alcohol, the second had limited access to alcohol and the last had no contact with alcohol.

“Our goal is to uncover potential new molecular targets that can be used to distinguish these types of pain and potentially be used in the future for the development of therapies,” said Nicoletta Galeotti, another author of the study. study, according to The Independant.

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