2023-06-04 14:00:00
The analysis of DNA not only improves the diagnosis, but it is also the promise of new treatments, in particular in the field of cancer. Objective in both cases: to personalize support as much as possible. First track followed: search, in the plasma, for pieces of DNA released by tumor cells when they die. Enough to reveal the presence of cancer even before the appearance of first symptoms. This line of research is the most desirable, but also the most complex. “If the tumor is still in its initial stage, so tiny, the amounts of this circulating tumor DNA [ADNtc] are so weak that they remain undetectable by current instruments”, says Patrizia Paterlini-Bréchot, professor of oncology and cell biology at the University of Paris-Descartes.
For her part, the specialist and her team have developed a test, called ISET, which consists of a very precise filtering of rare cells circulating in the blood, including tumor cells, making it possible to identify an incipient cancer. “It’s a revolution. We will soon be able to detect the passage of a person from the status “without cancer” to “in the process of developing cancer” and to offer him a personalized treatment”, assures Patrizia Paterlini-Bréchot.
All over the world, researchers are working on the development of so-called theranostic tests (combination of “therapeutic” and “diagnostic”): these analyze genetic abnormalities in (…)
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#Genomic #medicine #revolution #cancer #research #treatment
