Understanding the Link Between Growth Hormone Therapy and Alzheimer’s Disease Development

2024-02-29 16:37:08

Alzheimer’s disease typically results from the accumulation of a pathogenic form of beta-amyloid proteins in the human brain. It is noted that its cause is the accumulation of mutations in older age, and the presence of a hereditary defective gene can also lead to this disease.

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At the same time, in fresh publications V Nature Medicine Experts have reported on a number of cases in which Alzheimer’s disease developed as a result of medical intervention that occurred long before the patients showed the first signs of the disease. Thus, the disease developed as a result of the transmission of a pathogenic form of the corresponding proteins.

The research paper looked at eight patients who were treated with cadaveric growth hormone as children. The age of the subjects ranged from 38 to 55 years. Five of them had symptoms of dementia and had already been diagnosed with Alzheimer’s disease. Another patient qualified for this disease due to a combination of cognitive impairments.

Treatment with growth hormone from dead people, combined with a fairly young age at which the disease developed, allowed scientists to conclude that Alzheimer’s disease in patients was not sporadic or hereditary. They believe that its development is due to the transmission of a pathogenic form of beta-amyloid. At the same time, the risk of new cases of transmission of the disease in this way is absent today due to the fact that therapy with growth hormone of cadaveric origin is no longer practiced.

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