“Uncontrolled High Blood Pressure Linked to Dementia: Importance of Screening and Control”

2023-05-29 01:30:23

29 May 2023 – Prof. Dr. Teerawat Hemajutha, Head of Emerging Disease Health Sciences Center Faculty of Medicine Chulalongkorn Hospital Posted a message on Facebook saying 30 to 40 high blood pressure not managed. Dementia for sure

high blood pressure It is a silent threat that people rarely pay attention to. There is often a misunderstanding that there is no headache. You don’t need to measure the pressure.

without that headache It is because the blood pressure is gradually increasing. climb up the level little by little There will be no abnormal symptoms at all, and finally The soft veins will start to harden with or without tartar. and lead to coronary artery stenosis, heart attack Cerebrovascular clogging causes paralysis

In which this villain accumulates for 10 years and then reveals itself

High blood pressure causes changes in the brain. There has been more and more clear evidence. from brain computer examination in various ways A clear link was found between uncontrolled high blood pressure between the ages of 30 and 40 and Alzheimer’s pathology. and other dementias and abnormal changes in the white matter of the brain

by measuring the movement of water along the fibers of the brain from one location to another (fractional anisotropy), the efficiency of controlling the blood supply to different parts of the brain in each situation and spaces around the blood vessels in the brain that acts as a drain for waste from the brain and the amount of free water

changes in brain tissue, cranial fibers, and blood vessels in the brain These abnormalities accumulate over time. Since middle age that does not control blood pressure by age from 30 to 40 years

high blood pressure At the top level is 130 and the bottom is 80, where in Americans it is estimated that there are at least 44 to 46% of people with high blood pressure, with men found more than women. But when the age is over 65 years, women will begin to find that they have higher blood pressure than men. due to menopause lack of estrogen

Knowing and realizing the importance of controlling blood pressure in the first place It will greatly reduce the burden of having to take care of health.

The study, reported in the Journal of the American Medical Association JAMA network open April 3, 2023, used data from the kaiser healthy aging and diverse life experiences (KHANDEL) project and the study of healthy aging in African Americans (STAR).

by gathering the entire population of Asia Blacks, Caucasians, and Latinos. It was hypothesized that hypertension occurring between the ages of 30 and 40 would affect dementia biomarkers. and stability in the white cerebral cortex, which is mainly composed of nerve fibers.

by brain computer imaging assessment

Study population from both projects It began to be evaluated between 1964 and 1985 and has been monitored ever since. Until 2017 and 2021, there were 427 people in this study.

The study found that Elderly people, regarding 75 years old, especially in men. There will be abnormalities in the brain. If there is uncontrolled high blood pressure between the ages of 30 and 40 compared to people without high blood pressure.

The obvious anomaly is There is a collapse in the volume of the cerebral cortex, including the frontal and temporal lobes, resulting in a decrease in the volume of the cerebral cortex. and showed that the ventricles of the brain were larger and abnormalities in the white matter of the brain It was measured by efficiency in brain connectivity and free water as mentioned above.

This study, although the population is not much. But it has a good following. Although there may be limitations to the brain computer study. be done at a single point in time

But the results of the study May show differences between males and females. Women looked at the possibility that estrogen might protect once morest the effects of high pressure on brain atrophy. until when the hormones are depleted, and females appear to have differences in the location of their brains affected by pressure compared to males.

A 5 mm increase in systolic blood pressure was associated with decreased temporal cortex volume, while a 5 mm increase in systolic pressure was associated with parietal lobe wrinkling. (parietal cortex)more

The results of this study are consistent with reports that analyzed regarding 30 studies that found high blood pressure at a young age. Associated with degeneration of the frontal, temporal, and parietal lobes of the brain. and the inner temporal lobe called the hippocampus. which is the storage of current memory or short-term memory And several other studies have also found a correlation with changes in the white matter of the brain.

all these ensembles Indicates the importance of screening. or screening for health conditions from young people who will reach the age of 30 and hurry to control

This does not mean only the pressure. It’s regarding weight, what we call BMI, fitness condition. attention to exercise

Must never initiate smoking and, if still smoking, must quit immediately called broken Because no one dies from breaking raw cigarettes.

If you can’t drink alcohol, you don’t have to start. If drinking, the amount can be reduced to a healthy drink, which is no more than 30 grams per day, can be calculated from the percentage of alcohol. per volume of drink and get as close to vegetarianism as possible

That’s all, Thailand, the Thai people will be wealthy and do not have to waste the country’s budget. to treat Thai people who are full of sick people And plus, when will we be able to deal with toxic dust, air pollution and food from chemical contamination?

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