2023-05-17 06:33:41
When these nutrients are absent, researchers have found a overproduction of a molecule called TGF-beta in the epidermis of mice. And this overproduction disrupts the normal functioning of a category of immune cells, the Langerhans cells, exclusively present in the skin and functioning as a “modulator of cutaneous immune responses”.
The scientists then showed that compounds that activate the AhR receptor also control the production of TGF-beta in human skin cells.
“Our results suggest thatan unbalanced diet may increase allergic skin reactions in humans“, commented Elodie Segura, Inserm researcher who led this study at the Institut Curie, quoted in a press release.
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