2024-08-07 03:45:04
The stakes are high. nearly half Taking action from childhood on fourteen risk factors can prevent or delay the onset of dementia. This is the conclusionA study published in the journal lancet Wednesday, July 31st. This work is in Alzheimer’s Association International Conference (AAIC 2024)established by the Council on Aging lancet 2017. Twenty-seven experts pored over the literature and calculated the relative risk of developing Alzheimer’s disease for each risk factor.
The number of people living with dementia is expected to nearly triple by 2050. Alzheimer’s disease affects approximately 50 million people and is the leading cause of dementia.
amyloid plaque deposition
In light of the latest work, the committee’s experts listed two new risks: hypercholesterolemia from the age of 40, which causes 7% of dementia cases, and untreated vision loss later in life (2%) .
These are in addition to 12 risk factors previously identified in 2020: low education, hearing loss, high blood pressure, smoking, obesity, depression, sedentary lifestyle, diabetes, excessive alcohol consumption, head trauma, air pollution and social isolation. They are responsible for 40% of dementia cases.
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The article emphasizes that multiple new meta-analyses launched this year have shown that high concentrations of low-density lipoprotein cholesterol (bad cholesterol) in middle age are a risk factor for cognitive decline and dementia. This increases the deposition of amyloid plaques in the brain. “So far, research on the link between cholesterol and dementia risk has been divided. New research suggests that cholesterol, like high blood pressure, must be treated early.Philippe Amouyel, director of the Alzheimer’s Foundation and aging expert, emphasized.
“Strengthen prevention efforts”
Another new risk factor: untreated vision loss. The author relies on “Lots of new data”included a meta-analysis of fourteen prospective cohort studies. To be more precise: Studies show that people with cataracts who receive treatment can reduce their risk of developing dementia.
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