Benefits of high blood pressure therapy are quickly lost
Intensive action to get a systolic blood pressure less than 120 mmHg while protecting once morest cardiovascular disease, premature death and the development of cognitive impairment, it is possible Protective effect quickly lostif the measures are not further followed.
In a new secondary analysis of SPRINT Study (Systolic Blood Pressure Intervention Trial) with the participation of experts from the University of Minnesota investigated the long-term effects of hypertensive therapy on cardiovascular and all-cause mortality. The results can be found in the journal “JAMA Cardiology“ to be read.
treated blood pressure of 9,361 participants
In the original SPRINT study, 9,361 people with high blood pressure examined, which were already at least 50 years old. The participants were randomly assigned to one of two groups.
The first group aimed to achieve a systolic blood pressure target of less than 120mmHg to achieve what as one intensive treatment was viewed. The second group, on the other hand, pursued the goal of a systolic blood pressure of less than 140mmHgwhat as standard treatment was considered.
The SPRINT study has already established that participants who are under high blood pressure suffered, a reduction in systolic blood pressure to less than 120 mmHg with beneficial effects on the mortality was connected.
For example, a blood pressure of less than 120 mmHg reduced the rate of cardiovascular events such as von heart attacksheart failure and strokes a 25 percent.
In addition, such treatment was also associated with an order 27 percent associated with a lower risk of premature death compared to a systolic blood pressure of 140 mmHg.
Blood pressure rising once more over time
Finally, in the current secondary analysis of the study, the data of the National Death Index included and also analyzed the electronic health files of the participants for outpatient blood pressure measurements.
In this way, the researchers wanted to identify the long-term effects of intensive treatment of blood pressure. “The results are disappointing but not surprising‘ reports the author of the study Dr. Nicholas Pajewski in a press release.
„In addition to a diminishing benefit of intensive care treatment for cardiovascular mortality, we observed a gradual increase in blood pressure in the participants in the intensive care group, such that four or five years following the end of the study, there seemed to be no difference between the groups in systolic blood pressure“, explained Dr. Pajewski.
This makes it clear that simply monitoring and treating high blood pressure for a few years is not enough. Treating high blood pressure is one lifelong task represents. Maintaining and adjusting therapy to a target below 120 mmHg is critical to reducing cardiovascular mortality in the population.
According to Dr. Pajewski one sustained treatment and monitoring of blood pressure needed to reduce the risk of developing fatal cardiovascular events to further reduce. (as)
Author and source information
This text corresponds to the specifications of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.
Sources:
- Byron C. Jaeger, Adam P. Bress, Joshua D. Bundy, Alfred K. Cheung, William C. Cushman, et al.: Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control; in: JAMA Cardiology (veröffentlicht 12.10.2022), JAMA Cardiology
- Atrium Health Wake Forest Baptist: Study Highlights Importance of Long-term Management of Hypertension (veröffentlicht 12.10.2022), Atrium Health Wake Forest Baptist
Important NOTE:
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.