2023-08-22 22:14:00
The Department of Disease Control indicates that smallpox patients in Thailand are still West African species that are less virulent than the Central African species that still need to be monitored Reiterate that people with HIV do not receive antiretroviral drugs. very low body immunity Easily prone to complications But recently, there is good news that the World Health Organization sent medicines to treat infected people. Smallpox, especially monkeys, for 100 Thai people to use in order to study and collect data on side effects in HIV-infected patients as well.
At the Ministry of Public Health on August 22, Dr. Chakrarat Pittayawonganon Director of the Division of Epidemiology, Department of Disease Control, gave an interview to patients with smallpox (MPox) in Thailand, most of whom were infected with HIV infection (HIV). Currently, two strains are classified: West African (clade 2) and Central African (clade 1) strains with severe disease. cause more deaths Currently, smallpox monkeys in Thailand are still West African species. with less violence the chance of death is less But still need to watch out for Central African species. In case of smallpox monkey infection with HIV infection, it will be divided into 2 groups: those who are infected with HIV but receive antiretroviral drugs; able to control the level of immunity to be within normal limits When infected with smallpox monkeys, the symptoms of smallpox are pustules, similar to small abscesses. distributed throughout the body and HIV patients with opportunistic infections very low body immunity Risk of complications such as pneumonia, fungal or bacterial encephalitis When infected with monkey pox, it will make the pustules become larger in clusters with a large number of abscesses. Death can be caused by HIV. but with the nature of being infected with smallpox monkeys as well This makes the symptoms that show up more than patients who are not co-infected with HIV or who are infected with HIV but can be controlled. Therefore, it was not possible to clearly determine which virus died from which virus.
Dr. Chakrarath said that Treatment of HIV-positive infected monkeys with smallpox It will be used in conjunction with anti-HIV drugs. But there is currently no specific treatment for smallpox monkeys. However, the World Health Organization (WHO) is currently studying the use of a drug to treat smallpox infections, specifically called Tecovirimat or TPOXX, which has only 1 drug from a single manufacturer. In Thailand, 100 people have received the drug. Currently, it is in the process of using and collecting data at Bamrasnaradura Infectious Diseases Institute. The criterion for smallpox monkey patients to receive the drug is have HIV infection with low immune levels There are complications from opportunistic diseases. People with pneumonia Which this drug is oral type, 1 patient takes only 2 times, however, data on actual use in Thailand is still in the process of collecting Including information on side effects from taking the drug. For risk-free monkey pox patients Symptomatic treatment can be used. The disease takes regarding 2-4 weeks to heal and will disappear on its own.
As for the risk of infection with smallpox monkeys with those who live in the house with the infected person. Dr. Chakrarath said that Thailand currently has no infection in the household. All of them were infected by contact. Or live together and have sex together The risk is divided into 3 levels: 1. Intimate contact, such as sexual activity. even wearing a condom can become infected because the patient’s pustules may touch the skin cause infection 2. close contact, such as sharing a bed share a bathroom Being close to each other or just holding hands The risk will be reduced and 3. indirect contact, such as patients going to sleep in a hotel Then the staff came to clean the room. A general feast that is not so close that they snuggle together. eating together at the table
Dr. Sophon Iamsirithaworn The Deputy Director-General of the Department of Disease Control said that for anti-monkey smallpox virus drugs It was originally registered in Europe in 2022 for the treatment of smallpox in humans (Small pox), but when smallpox was found in monkeys. have been used to treat It turned out to be effective. It has been used with smallpox monkeys. which the World Health Organization has conducted a research project on this drug in Thailand is 1 of approximately 10 countries that have received this drug for use and data collection
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