2023-09-22 04:00:04
A new chapter opens in the fight once morest the dreaded Staphylococcus aureus, better known as “Staphylococcus aureus”. Australian researchers unveil the genetic mysteries of this bacteria, shedding light on why it is dangerous when it enters the bloodstream.
Credit: Public domain CC0
Staphylococcus aureus is common but can become fatal in cases of sepsis (formerly called sepsis). In addition, this bacterium (Bacteria (Bacteria) are prokaryotic unicellular living organisms, characterized…) is infamous for its resistance to antibiotics, which greatly complicates its treatment.
Led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), a team of researchers analyzed more than 1,300 strains of Staphylococcus aureus. The study was published in the journal Cell Reports and uses a technique called genome-wide association study (GWAS).
Dr. Stefano Giulieri, from the University of Melbourne and first author of the article, highlighted the importance of data. genomics in diagnosis (The diagnosis (from the Greek δι?γνωση, diágnosi, from…). “GWAS makes it possible to examine the genome (The genome is all of the genetic material of an individual or a…) many bacteria to identify mutations linked to specific characteristics, such as antibiotic resistance,” he explains.
Professor Ben Howden, also from the University of Melbourne and co-senior author of the study, considers these findings a significant advance in medical research. (Medical research is divided into basic and clinical research.). They offer new avenues for the development of therapeutic solutions once morest Staphylococcus aureus infections.
By combining clinical, genomic and antibiotic data, the study made it possible to determine that certain genes are directly linked to antibiotic resistance and the persistence of the bacteria in the blood (Blood is a liquid connective tissue made up of cell populations free, including…). This knowledge might be the key to personalizing treatments according to the genetic profile of each infecting strain.
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