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Obesity is the gateway to diseases such as diabetes and various cardiovascular disorders.
7/3/2023
According to a study carried out by researchers at the Shibaura Institute of Technology (Japan), “a new way to combat obesity and associated diseases was found using a known substance, vitamin E”, as explained by the portal The reason.
In the analysis published in the journal Molecules and led by Professor Koji Fukui found that “tocotrienols (T3), a subtype of vitamins E, were successful in both preventing obesity and reducing ‘bad cholesterol’”.
Professor Fukui indicated that in general terms “the results suggest that a higher intake of tocotrienols from daily foods may be effective in preventing obesity”, in words that the portal collects The reason.
The portal Notice log he also cites the study conducted in Japan. “The new study performed several experiments with mice. One group ate a high-fat diet, another group received a high-fat diet and was treated with T3, and two other groups were fed a control diet with or without associated T3.”
Similarly, Professor Ken Sato, who works in the Department of Internal Medicine, Aichi Medical University, Nagakute, Japan, and his team conducted a meta-analysis to examine the beneficial effect of vitamin E on heart disease. non-alcoholic fatty liver (NAFLD), including non-alcoholic steatohepatitis (NAFLD).
The aim of that study was to assess the efficacy of vitamin E in improving liver function. Professor Sato concludes in his report that “this meta-analysis indicates that treatment with vitamin E improves serum biochemical parameters and liver histology in NAFLD/NASH; in adult NASH patients; especially, vitamin E also improves fibrosis, inflammation and hepatic ballooning”.
NAFLD is often associated with the usual effects of metabolic syndrome, ie obesity, insulin resistance, and type 2 diabetes (T2D). However, NAFLD, which encompasses several disorders, has become a major health problem and is the most common liver disease worldwide. It is estimated that its prevalence is around 20-30% of the general population and up to 70-80% of obese people, but only between 16 and 20% of people with normal weight.
On the other hand, the histological pattern of NAFLD can degenerate into NAFLD, liver fibrosis, cirrhosis, and also hepatocellular carcinoma. Antioxidant therapy in the form of vitamin E has been considered beneficial in the treatment of NASH, but further work was needed to fully understand the data.
Therefore, this analysis might have a significant impact on public health, since NAFLD is also considered a risk factor for cardiovascular disease, T2D, and chronic kidney failure.
However, although vitamin E has often been used in the treatment of NAFLD/NASH, the magnitude of the response associated with vitamin E in improving liver function and histology in these conditions has not been systematically quantified.
However, in the study, Professor Sato used very strict inclusion and exclusion criteria to avoid possible inaccuracies. For this reason, the list of relevant publications included in the meta-analysis was reduced to five. The meta-analysis concluded that vitamin E therapy may reduce the level of liver damage associated with hepatitis and cirrhosis in children and adults with NAFLD and NASH.
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