2023-12-01 10:54:26
Today (1 Dec. 2023) on the side of “Ajarn Jesada Denduangboriphan” posted on Facebook “Oh, it’s like this” by Achan Jesat saying
“IARC does not say that caramel color E-150d is carcinogenic to humans.”
Someone sent this picture for me to look at. Along with the question, is it true or not? that E-150d is a carcinogen in humans According to a review conducted by IARC, the WHO’s International Agency for Research on Cancer (World Health Organization), the dye ammonium sulfite (E-150d) was classified among 249 substances that may Causes cancer in humans!? Like this, I can’t eat cola anymore, Teacher!?
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The answer is that it is not true. IARC does not classify E-150d, which is a food coloring made from caramel. (That is, take sugar and roast it. causing a burnt brown color) is a substance that may cause cancer in humans…
It’s just that in the production process of this caramel dye group (there are many), a new substance named 4-MEI or 4-Methylimidazole may occur, which is a separate substance that IARC has classified in group 2B, which is Possibly carcinogenic to humans. (Check at the website)
But being in group 2ฺB means being in a group that has some evidence in experimental animals. But there is still no clear evidence in humans.. which evidence It will come from exposing lab rats to ingesting large amounts of this substance for a long time (even though the amount actually put in food or soft drinks is very small).
According to the information in Wiki (indicating that there was an experiment where rats were exposed to this substance 4-MEI in large quantities (40 milligrams or more per kilogram of body weight) every day for 2 years in a row, so there were more lung tumors. And those who get very large amounts (170 mg. per kilogram of body weight) will develop tumors. The type that can lead to lung cancer
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4-MEI may be formed in the production of group 3 (E-150c) and group 4 (E-150d) caramel food coloring during the heating of sugar and nitrogen groups. To start the process of creating caramel. European Food Agency Therefore, it has been determined that the level of 4-MEI in caramel food coloring, numbers E150c and E150d, must not exceed the limit, which is not more than 200 and 250 milligrams per kilogram of caramel color E150c and E 150d, respectively (at the level color intensity equal to 0.1)
While the US Food Agency has set a limit of no more than 250 mg/kg of caramel food coloring, the FDA believes there is no acute danger from short-term exposure to 4-MEI.
For Thailand we It is also allowed to use food and drink coloring. The caramel color group is already classified as a “natural color.” For example, in the snack food group, Allowed to use caramel color, code INS-150d or group 4 caramel color, sulfite ammonia caramel. The maximum amount allowed as an adulterant in food is up to 5000 mg/kg of food and the code INS-150c or caramel color group 3, ammonia caramel. The maximum amount allowed as an adulterant in food is up to 5000 mg/kg of food as well (from http://alimentum.fda.moph.go.th/…/Additive/CodexDetail…)
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In summary, although the food coloring E150d or Sulfite ammonia caramel has been found to contain 4-MEI, which has been shown to cause cancer in rats. But it must be when the laboratory rats receive a large amount. And for a long time As a result, food agencies of various countries consider this caramel food coloring to be at very low risk of causing cancer in humans. And there is no need for a warning on the product label. Only the producing company must control the amount of 4-MEI not to exceed the limit.
Source credit: FB : Oh, it’s like this. by Acharn Jess.
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