The treatment of aging.. some medicines are in our hands without realizing it

world’s adults aged 65 or over suffer from Chronic disease At least one, while 68 percent have two or more diseases.

The human suffering is enormous, and in the next 30 years, the number of people over the age of 65 is expected to double to 1.5 billion, according to the website. "Science Fox".

Nir Barzilai, director of the Institute on Aging at New York Medical School, says: "There are a lot of people selling you snake oil and telling you that you will live forever, and then when you die, no one will sue them"But the real anti-aging medicine out there is regarding improving what scientists call it "health period"or the number of years people can live well without disease.

Anti-aging medicine

Although the idea of ​​a drug that "Extends life and prevents aging" It seems far from the truth, but mounting evidence indicates that these drugs are within reach, and some of them already exist.

Some anti-aging medications can be found on the shelves at your local drugstore, while others are reusable medications for conditions like diabetes and cancer.

Wolfa expected "Science Fox"Animal studies have demonstrated the potential of anti-aging drugs, and now clinical trials are beginning to assess whether their promise is true in humans.

If this is achieved, middle-aged people might now be the first generation to benefit from its use.

Also encouraging is the fact that these drugs are already known to be safe for human use. For example, quercetin, a plant pigment found in many fruits and vegetables, is sold as a dietary supplement, while dasatinib is approved for use as a leukemia drug.

In December 2021, researchers from the University of the Chinese Academy of Sciences in Shanghai revealed that a natural compound found in grape seeds can extend the life of old mice by 9 percent, and also make them fitter.

This compound targets the buildup of tired and worn out cells that are described as "aging"These are available to users via quercetin, a plant pigment found in many fruits and vegetables, as a dietary supplement.

In our younger years, the immune system would remove aging cells from the body before they might cause a problem, but as we age and our immune system falters, the cells roam and secrete inflammatory molecules that infect surrounding tissues.

says Ming Shu, who studies aging At the University of Connecticut Center on Aging: "Like a fire that spreads… very few cells, but it has a very large and very destructive effect."

aging treatment

Drugs that seek out and kill these aging cells are known as "sinolatex"It is among the most promising anti-aging treatments.

Synolatex’s drugs include quercetin, a plant pigment found in many fruits and vegetables, as a dietary supplement, and dasatinib, which is approved as a drug for leukemia.

Studies conducted on animals have shown that "sinolatex" It can delay, prevent or mitigate more than 40 diseases, including cancers and various disorders of the heart, liver, kidney, lung, eye and brain.

All of these trials will provide vital information, but if a drug is approved "sinolatex" Or any other drug as a true anti-aging treatment, it would need to pass the human trial, in addition to testing these drugs on people who are already infected, and rigorously testing them on healthy people who age naturally.

dog experiences

On the other hand, extensive experiments are conducted on dogs, which live in an environment similar to humans, to arrive at Anti-aging medicine.

As part of the US Dog Aging Project, 500 dogs contribute to an evaluation of the value of another putative anti-aging treatment called rapamycin. This drug also targets aging cells, in addition to many other features of aging.

In small doses, it has been shown to extend lifespan in yeast, worms, flies and mice. The dogs will be followed for up to a decade, and if the promise of rapamycin is fulfilled, those who receive the treatment might extend their lives by up to four human years.

Huge experience

As scholars in Britain recruited 3,000 adults, ages 65 to 80, who did not have diabetes, to receive metformin over four years, a promising anti-aging drug.

During this time, the team will monitor age-related biomarkers and the time it takes for each patient to develop a major age-related disease, such as dementia or stroke.

Rather than looking at metformin’s ability to delay a single age-related disease, as other trials have done, this study will evaluate the drug’s ability to delay the onset of age-related disease in general. It will be shown whether metformin can extend a healthy lifespan.

In the end, treatment for Synolatex, metformin, rapamycin, and other yet-to-be-identified anti-aging drugs might be part of an overall change.

It would be a shift away from the mainstream medical model, where diseases are treated reactively following symptoms appear and suffering begins, to a preventive model of care, where patients are proactively monitored and future diseases averted.

“>

Currently, 80 percent of the world’s adults aged 65 or over suffer from Chronic disease At least one, while 68 percent have two or more diseases.

The human suffering is enormous, and in the next 30 years, the number of people over the age of 65 is expected to double to 1.5 billion, according to Science Fox.

“There are a lot of people selling you snake oil and telling you you’re going to live forever, and then when you die, nobody sue them,” says Nir Barzilai, director of the Institute on Aging at New York Medical School. But the real anti-aging medicine out there is regarding improving what he calls Scientists have a “period of health,” or the number of years people can live well without disease.

Anti-aging medicine

Although the idea of ​​a drug that “prolongs life and prevents aging” seems far from the truth, mounting evidence indicates that these drugs are within reach, and some of them already exist.

Some anti-aging medications can be found on the shelves at your local drugstore, while others are reusable medications for conditions like diabetes and cancer.

According to the “Science Fox” website, animal studies have demonstrated the potential of anti-aging drugs, and now clinical trials are beginning to assess whether their promise is real in humans.

If this is achieved, middle-aged people might now be the first generation to benefit from its use.

Also encouraging is the fact that these drugs are already known to be safe for human use. For example, quercetin, a plant pigment found in many fruits and vegetables, is sold as a dietary supplement, while dasatinib is approved for use as a leukemia drug.

In December 2021, researchers from the University of the Chinese Academy of Sciences in Shanghai revealed that a natural compound found in grape seeds can extend the life of old mice by 9 percent, and also make them fitter.

This compound targets the buildup of tired, worn out cells described as “aging” and is available to users via quercetin, a plant pigment found in many fruits and vegetables, as a dietary supplement.

In our younger years, the immune system would remove aging cells from the body before they might cause a problem, but as we age and our immune system falters, the cells roam and secrete inflammatory molecules that infect surrounding tissues.

says Ming Shu, who studies aging At the University of Connecticut Center on Aging: “It’s like a fire that spreads…too few cells, but it’s too big, too devastating.”

aging treatment

Drugs that seek out and kill these aging cells, known as ‘synolates’, are among the most promising anti-aging treatments.

Synolatex’s drugs include quercetin, a plant pigment found in many fruits and vegetables, as a dietary supplement, and dasatinib, which is approved as a drug for leukemia.

Animal studies have shown that Synolatex drugs can delay, prevent or mitigate more than 40 diseases, including cancers and various disorders of the heart, liver, kidney, lung, eye and brain.

All of these trials will provide vital information, but if Synolatex or any other drug is approved as a true anti-aging treatment, it will need to pass the human trial, in addition to testing these drugs on people who are already infected, and rigorously testing them on healthy people who age naturally. .

dog experiences

On the other hand, extensive experiments are conducted on dogs, which live in an environment similar to humans, to arrive at Anti-aging medicine.

As part of the US Dog Aging Project, 500 dogs contribute to an evaluation of the value of another putative anti-aging treatment called rapamycin. This drug also targets aging cells, in addition to many other features of aging.

In small doses, it has been shown to extend lifespan in yeast, worms, flies and mice. The dogs will be followed for up to a decade, and if the promise of rapamycin is fulfilled, those who receive the treatment might extend their lives by up to four human years.

Huge experience

As scholars in Britain recruited 3,000 adults, ages 65 to 80, who did not have diabetes, to receive metformin over four years, a promising anti-aging drug.

During this time, the team will monitor age-related biomarkers and the time it takes for each patient to develop a major age-related disease, such as dementia or stroke.

Rather than looking at metformin’s ability to delay a single age-related disease, as other trials have done, this study will evaluate the drug’s ability to delay the onset of age-related disease in general. It will be shown whether metformin can extend a healthy lifespan.

In the end, treatment for Synolatex, metformin, rapamycin, and other yet-to-be-identified anti-aging drugs might be part of an overall change.

It would be a shift away from the mainstream medical model, where diseases are treated reactively following symptoms appear and suffering begins, to a preventive model of care, where patients are proactively monitored and future diseases averted.

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