The root of the Rhodiola rosea plant is the subject of discussions as to its possible action once morest type 2 diabetes. According to reports published by the University of California-Irvine, the root extract of this plant might prove to be “a safe and effective non-pharmaceutical alternative”. The study was published in Scientific Reports.
The genetically modified mouse experiment
The experiments were performed on genetically modified mice, a condition similar to human type 2 diabetes. The mice were characterized by obesity, insulin resistance and high blood sugar, all characteristics found in humans with type 2 diabetes. The researchers divided the mice, male and female and all of the same age, into two groups: the control group, whose members received only water, and the group whose members consumed Rhodiola rosea extract.
Discoveries
Researchers have found that the plant extract may be useful in treating type 2 diabetes in humans. The root extract of this herb, in particular, appears to alter the microbiome and promote greater gut barrier integrity. The same extract also appears to reduce the “translocation of inflammatory molecules into the bloodstream”, as reported by Mahtab Jafari, professor of pharmaceutical sciences at UCI and corresponding author of the study. According to the scientist, the integrity of the intestinal barrier can determine not only body weight but also insulin response. Rhodiola rosea root extract can cause the liver and muscle tissues to respond more effectively to insulin secreted by the pancreas.
The end goal is to conduct experiments on humans
The researchers now want to carry out more comprehensive studies on mice with obesity-induced diabetes in order to also understand the underlying molecular mechanisms. The end goal is to conduct similar studies in human patients with type 2 diabetes. “Current treatment recommendations include lifestyle changes and oral and intravenous medications. However, these drugs have significant limitations or side effects, which increases the need for new therapeutic interventions,” explains the researcher.
What is Rhodiola rosea?
Rhodiola rosea is a succulent plant belonging to the Crassulaceae family. The name is partly due to a particular scent reminiscent of roses that emanates from the rhizome of this plant.
Where does Rhodiola rosea grow?
Rhodiola rosea is mainly found in high mountain areas, especially in barren and stony areas or in pastures. It is mainly found between 900 and 3100 meters above sea level. It is found in the Pyrenees, Alps, Vosges and other mountainous regions of Europe.
