2023-08-19 10:52:23
According to a scientific study, this “universal” antibody might allow treatments capable of destroying cancer cells.
The NP137 antibody “gives a lot of hope to arrive at a treatment that can be positioned in several therapeutic indications”that is to say for different diseases, believes Professor Alain Toledano, oncologist, radiotherapist and founding president of the Rafael Institute, a “house of post-cancer”. According to a study published in the scientific journal Nature by CNRS researchers, this antibody “universal” would be able to defuse a resistance mechanism shared by most cancer cells.
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What is this antibody and how does it work?
Each cancer cell is unique and presents itself differently. But on most cancer cells there are certain receptors like locks, for which we are constantly looking for keys to prevent cancer cells from growing. This protein that we discovered will allow us to have treatments to destroy cancer cells.
What impact can this have on these cancer cells?
Cancer cells feed on their environment. They feed on signals and what they want is to grow, to reproduce. From the moment we understand their mechanics, the way in which they develop, our job will be to prevent them in order to manage to ensure that they do not develop, that they do not metastasize and that we can destroy them.
On which cancer is this NP137 antibody the most effective?
Thanks to a team from Lyon, we have studied the presence of these proteins in many cancers (colorectal, lung cancer, gynecological cancer) and other rarer diseases such as sarcomas and blood diseases. And we noticed that there was a similarity in all these cancers, so it gives a lot of hope to arrive at a treatment that can be positioned in several therapeutic indications.
Do we know the side effects of its use?
This is an excellent question because each time we talk regarding new treatments, we hope for their effectiveness and we want them to be well tolerated. Before a drug comes on the market, it must be seen whether the human body tolerates it. In the first tests, it was shown that the tolerance was satisfactory, that the drug was tolerated, so you can live with this drug. It gives us a lot of hope to start positioning ourselves
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