2024-05-31 12:35:29
Immersion in scientific disciplines which, quietly, curiosity start-ups and personal clinics for the larger well-being of the tremendous wealthy.
It’s by taking a tour of the world of longevity clinics that we uncover practices like nutrigenomics. These clinics which promise their rich purchasers to battle in opposition to the getting old course of, say they depend on this science which is supposedly essentially the most superior on this subject. So Simon Gibertonicommon director of La Prairie, essentially the most well-known longevity clinic positioned in Montreux, Switzerland, states that the clinic’s scientific committee is made up of “main researchers, clinicians and advisors of their respective fields: longevity, neuroscience, genetics, biostatistics, nutrigenomics , biosciences and immunology. »
Thibault Sutter, physician in physiology, is aware of the La Prairie clinic nicely, the place he has already labored. He who resides in Annecy continues to officiate in Switzerland, on the clinic of way of life medication Medinvita from Geneva. There he develops analysis on the nutrigenetics and synthetic intelligence. Why the selection of Switzerland? The reason being easy: “We’re not presently allowed to work on DNA in France. » His long-term dream is to discovered his personal longevity clinic. For the second, he’s being contacted by clinics being established all around the world, with a view to discovered anti-aging facilities. The most recent one is in Bratislava. “Clinics that don’t develop on the nutrigenetic side, for me, are lacking the purpose,” he says.
Nutrigenomics, nutrigenetics, what precisely are we speaking about?
Nutrigenomics like nutrigenetics fall underneath the dietary genomicsa self-discipline that research the interactions between vitamins and genes. Walter Wahliprofessor emeritus of biology on the College of Lausanne and creator in 2011 of the ebook Nutrigenomics in your plate is the precursor. Whereas engaged on estrogen receptors within the Nineties, he found that fatty acids might, like estrogens, act on the activation of genes by the receptors. Later, it highlights comparable interactions for different micronutrients corresponding to nutritional vitamins. Nutrigenetics was born. She research how variations in a DNA sequence induce variability in particular person responses to vitamins (e.g. metabolism).
And epigenetics in all this?
Then comes the epigenetic revolution. Claudine Junien, professor emeritus of genetics, explains: “For years we have been solely curious about variations in DNA, however not in how genes labored. The epigenome is what permits genes to be expressed or silenced. And a number of other components are concerned on this course of.”
Amongst these components, the setting, but in addition… vitamin. Technological progress corresponding to genome sequencing within the early 2000s makes it doable to focus on the motion of vitamins on the epigenome, or the expression of genes: we then communicate of nutrigenomics. On the identical time, our DNA governs the way in which through which we react to this or that nutrient and, within the different route, our weight loss plan has the facility to activate, or not, the potential of our genes.
Clearly, the implications are appreciable. Sarah Dognin, physician of pharmacy, affiliate professor on the College of Lyon and nutritionist, makes use of the findings of nutrigenomics to supply personalised vitamin, primarily based on a “physique audit”. As gene expression isn’t mounted, consuming conduct takes a primordial place. “There are genes which, if activated, promote sure pathologies corresponding to BRCA1 or 2 for breast most cancers. However it’s only a potentiality, for those who use your physique poorly,” warns Sarah Dognin.
For Thibault Sutter, this goes additional than the prevention of pathologies: “nutrigenomics provides appreciable potential for rising longevity”. Therefore the very fact, he provides that “for 4-5 years, a number of start-ups like GlicanAge or 24Genetics, banned in France, have emerged and supply epigenetic checks which you can perform at house”.
Walter Wahli underlines the curiosity in persevering with analysis with a view to transcend the purely personalised side of epigenetic checks in order that “this could profit as many individuals as doable: for instance to search out out if Asians have a tendency to reply in another way to sure meals in comparison with Caucasians. »
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