The Impact of Social Isolation on Young-Onset Dementia Risk: Latest Research Findings

2023-12-27 12:23:12
On December 26, 2023, the latest research published in the Journal of the American Medical Association Neurology pointed out that social isolation will significantly increase the risk of developing young dementia. (Photo/Anthony Tran @Unsplash)

Nearly 4 million people worldwide develop symptoms of dementia before the age of 65, and 370,000 new patients are diagnosed every year. The latest research published in JAMA Neurology on the 26th found that 15 factors can significantly increase the risk of young-onset dementia, including alcoholism and loneliness.

The study, conducted by researchers from the University of Exeter in the UK and Maastricht University in the Netherlands, surveyed 350,000 people under the age of 65 from the UK Biobank. , to study factors that may influence the tendency of young people to develop dementia, including genetics, lifestyle, and environmental factors.

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The study found that 15 factors significantly increase the risk of young-onset dementia, including alcohol abuse, social isolation, depression, vitamin D deficiency, hearing impairment, low formal education or low socioeconomic status. The study authors said this is the first study to find that lifestyle changes can reduce the risk of developing dementia in the young adult population: “While further exploration of these risk factors is necessary to identify possible underlying mechanisms, addressing these modifiable factors Factors that may prove effective in mitigating the risk of dementia in young adults and can be easily incorporated into current dementia prevention approaches.”

Sebastian Köhler, lead author of the study and professor of neuroepidemiology at Maastricht University, said: “In addition to physical factors, mental health also plays an important role, including avoiding chronic stress, loneliness and depression. In fact, This was also evident in young-onset dementia, which surprised me and may also provide opportunities to reduce risk in this group.” (Recommended reading:Good news for people with dementia!Latest research: This new drug jointly developed by Japanese and American pharmaceutical companies can significantly reduce symptoms

Janice Ranson, a senior researcher at the University of Exeter, said the study “breaks new ground in identifying risks that can reduce the risk of dementia in young people, and we think it might herald a new era of interventions to reduce new cases of the disease.” advent”. Leah Mursaleen, head of clinical research at Alzheimer’s Research UK, which co-funded the study, said: “This ground-breaking research provides new insights into the impact of young-onset dementia. “The factors that underlie risk provide much-needed important insights that are beginning to fill important gaps in our knowledge, and it is important to build on these findings across a broad range of studies.”

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