Due to the advent of many new diabetes drugs such as Ozempic, the American Diabetes Association (ADA) has proposed new treatment guidelines, recommending that doctors use newer drugs first when prescribing drugs to treat patients, because the new order of medication is more difficult for patients Tailor-made, many diabetic patients must treat high blood pressure, kidney disease and obesity at the same time. After changing the order, it can not only reduce the patient’s weight, but also protect the heart and kidneys.
The Wall Street Journal (WSJ) reported on the 5th that the old treatment for diabetes started with a drug called metformin (metformin), which lowers the blood sugar level of patients. Marie McDonnell, chief of diabetes at Brigham and Women’s Hospital in Boston, said the new medication guidelines are a complete departure from the traditional approach to treating high blood sugar; doctors used to focus on lowering blood sugar because, following all, That’s all it can really do.
Newer diabetes drugs are abbreviated as sodium-glucose transporter type II (SGLT-2) and glucagon-like peptide-1 (GLP-1) according to their efficacy, and are more expensive than metformin; Nearly 900 yuan per month, Jardiance is regarding 590 yuan per month.
Studies have found that metformin, which was first approved for marketing in the United States in 1995, can reduce high blood sugar levels. However, many patients with type 2 diabetes need to treat heart disease, weight and pancreatic problems at the same time, and often have to use other drugs for treatment.
SGLT-2 inhibitors reduce blood sugar levels by preventing the kidneys from reabsorbing blood sugar, allowing blood sugar to be excreted in the urine.
The medical community says GLP-1 replicates the body’s natural response to diet to produce a hormone called glucagon-like peptide-1, which stimulates the production of insulin, which helps lower blood sugar. GLP-1 drugs also suppress people’s appetite, doctors say.
The Food and Drug Administration (FDA) began approving new types of diabetes drugs a few years ago; academics have linked Avandia, a diabetes drug, to heart attacks, and in 2008 the FDA recommended that drugmakers test their diabetes drugs to make sure they don’t Dangerously elevated risk of heart disease.
In 2021, the FDA approved Novo Nordisk’s GLP-1 drug called Wegovy to manage weight, and it also approved the drug to treat type 2 diabetes under the brand name Trituzan. The FDA has approved Eli Lilly’s Mounjaro to treat diabetes and is considering whether to allow the drug to treat obesity.
According to the new guidelines of the ADA, when doctors want to prescribe diabetes drugs, they should also consider whether the drugs increase the patient’s risk of heart attack, kidney disease attack, and weight gain, and then decide which drug to use.
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The advent of new diabetes drugs and the update of treatment guidelines also treat patients with heart, kidney and obesity
