What is the cause of the reduction in the incidence of peptic ulcer in recent years?
Table of Contents
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- 0.0.1 What is the cause of the reduction in the incidence of peptic ulcer in recent years?
- 0.0.2 What is the main reason for surgical treatment of peptic ulcer nowadays?
- 0.0.3 What are the elective surgical indications for peptic ulcer?
- 0.0.4 What are the urgent surgical indications for peptic ulcer?
- 0.0.5 What is the most common complication of peptic ulcer that requires surgery?
- 0.0.6 What factors increase the risk of perforation in peptic ulcer?
- 0.0.7 How does perforated gastroduodenal ulcer clinically manifest?
- 0.0.8 What diagnostic test should be performed if ulcer perforation is suspected?
- 0.0.9 What does surgical treatment of perforation consist of?
- 0.0.10 When can nonsurgical treatment for perforated ulcer be considered?
- 0.0.11 When is bleeding common as a complication of peptic ulcer?
- 0.0.12 What is the most common cause of upper gastrointestinal bleeding?
- 0.0.13 What is the treatment of choice for peptic ulcer bleeding?
- 0.0.14 What are the indications for surgically intervening on a bleeding ulcer?
- 0.0.15 What is the goal of surgery for ulcer bleeding?
- 0.0.16 When is elective surgical treatment for peptic ulcer considered?
- 0.0.17 How does pyloric stenosis manifest clinically?
- 0.0.18 What are the surgical options for treating pyloric stenosis?
- 0.0.19 When is surgery indicated for refractory ulcer?
- 0.0.20 What are the elective indications for surgical treatment of refractory ulcers?
- 0.0.21 What is the indicated surgical treatment for refractory gastric ulcer?
- 0.0.22 What is the technique of choice in treating a refractory duodenal ulcer?
- 0.0.23 What is the most important risk factor for peptic ulcer bleeding?
- 1 The Declining Incidence of Peptic Ulcers: Causes and Surgical Solutions
- 1.1 What is the Cause of the Reduction in the Incidence of Peptic Ulcer in Recent Years?
- 1.2 What is the Main Reason for Surgical Treatment of Peptic Ulcer Nowadays?
- 1.3 Elective Surgical Indications for Peptic Ulcer
- 1.4 Urgent Surgical Indications for Peptic Ulcer
- 1.5 The Most Common Complication of Peptic Ulcer that Requires Surgery
- 1.6 Factors Increasing the Risk of Perforation in Peptic Ulcer
- 1.7 Clinical Manifestations of Perforated Gastroduodenal Ulcer
- 1.8 Diagnostic Tests for Suspected Ulcer Perforation
- 1.9 Surgical Treatment for Perforated Ulcer
- 1.10 Non-Surgical Treatment for Perforated Ulcer
- 1.11 Bleeding as a Complication of Peptic Ulcer
- 1.12 Treatment of Choice for Peptic Ulcer Bleeding
- 1.13 Surgical Intervention for Bleeding Ulcer
- 1.14 Elective Surgical Treatment for Peptic Ulcer
- 1.15 Clinical Manifestations of Pyloric Stenosis
- 1.16 Surgical Options for Treating Pyloric Stenosis
- 1.17 Surgical Indication for Refractory Ulcer
- 1.18 Conclusion
The reduction is due to the decrease in the prevalence of infection by Helicobacter pylori and the effectiveness of its eradication treatment.
What is the main reason for surgical treatment of peptic ulcer nowadays?
The main cause is perforation, mainly caused by the widespread use of NSAIDs and ASA in an increasingly aging population.
What are the elective surgical indications for peptic ulcer?
The surgical indications for elective gastroduodenal ulcer are:
- Ulcer refractory or persistent to medical treatment;
- Suspicion of malignancy;
- Non-dilative stenosis.
What are the urgent surgical indications for peptic ulcer?
Urgent indications for gastroduodenal ulcer are:
- Hemorrhage not resolved endoscopically;
- Drilling.
What is the most common complication of peptic ulcer that requires surgery?
The most common complication is perforation, although hemorrhage is the most frequent complication.
What factors increase the risk of perforation in peptic ulcer?
Risk factors include:
- Tobacco;
- Taking NSAIDs and ASA;
- Consumption of cocaine and psychostimulants.
How does perforated gastroduodenal ulcer clinically manifest?
It manifests itself with sudden and intense epigastric pain, radiating to the shoulders, accompanied by nausea and vomiting, with signs of peritoneal irritation (“table abdomen”) and, in advanced cases, signs of sepsis.
What diagnostic test should be performed if ulcer perforation is suspected?
An upright chest x-ray should be obtained to observe the presence of pneumoperitoneum under the diaphragmatic domes.
What does surgical treatment of perforation consist of?
Treatment consists of closing the perforation, usually associated with omentoplasty and washing of the abdominal cavity. Usually, surgery is performed laparoscopically. In gastric ulcer, resection is performed for anatomopathological study.
When can nonsurgical treatment for perforated ulcer be considered?
This approach should be taken into consideration in very selected cases, with a haemodynamically stable patient, without peritonitis and signs of perforation without free air.
When is bleeding common as a complication of peptic ulcer?
This complication is present in 20-25% of peptic ulcers.
What is the most common cause of upper gastrointestinal bleeding?
Duodenal ulcer, usually located on the posterior surface.
What is the treatment of choice for peptic ulcer bleeding?
The treatment of choice is endoscopy, both diagnostic and therapeutic.
What are the indications for surgically intervening on a bleeding ulcer?
Indications include:
- Failure of endoscopic control;
- Severe hemodynamic impact;
- Need for more than 6 units of concentrated blood in 24 hours;
- Rebleeding after endoscopic hemostasis.
What is the goal of surgery for ulcer bleeding?
The goal is to stop the bleeding by suturing the bleeding vessel, suturing the ulcer, or resection of the ulcer, as appropriate.
When is elective surgical treatment for peptic ulcer considered?
Answer:
It is considered in case of evolving complications (such as pyloric stenosis) or failure to heal with medical treatment.
How does pyloric stenosis manifest clinically?
It manifests itself with early satiety, bloating, nausea, vomiting, epigastric fullness and often weight loss and malnutrition.
What are the surgical options for treating pyloric stenosis?
Options include:
- Pyloroplasty;
- Gastroduodenostomia (Finney);
- Truncular vagotomy associated with antrectomy.
When is surgery indicated for refractory ulcer?
Surgery is indicated when the ulcer persists after 8-12 weeks of correct treatment.
What are the elective indications for surgical treatment of refractory ulcers?
Elective indications include:
- Drug intolerance;
- Suspected unconfirmed cancer;
- Patients at risk of complications (transplant recipients, chronic users of NSAIDs or corticosteroids).
What is the indicated surgical treatment for refractory gastric ulcer?
Surgical resection is indicated as a surgical treatment to exclude gastric neoplasia if not cured after 12 weeks of treatment.
What is the technique of choice in treating a refractory duodenal ulcer?
The technique of choice is supraselective vagotomy, which can be open or laparoscopic.
What is the most important risk factor for peptic ulcer bleeding?
The most important risk factor is the use of NSAIDs.
The Declining Incidence of Peptic Ulcers: Causes and Surgical Solutions
Peptic ulcers, a common gastrointestinal ailment, have seen a considerable decline in incidence over recent years. This article explores the primary reason behind this decrease, examines the surgical treatment of peptic ulcers in modern medicine, and outlines specific indications for surgical intervention.
What is the Cause of the Reduction in the Incidence of Peptic Ulcer in Recent Years?
The significant reduction in the occurrence of peptic ulcers can largely be attributed to the decreased prevalence of Helicobacter pylori (H. pylori) infections, alongside the increased effectiveness of eradication treatments for this bacteria. H. pylori is a gram-negative bacterium that is often the primary culprit in the development of peptic ulcers, as it can weaken the stomach’s protective mucosa and lead to inflammation. With improved education, diagnosis, and treatment options, the rate of H. pylori infection has notably diminished, consequently lowering the incidence of ulcers.
Recent Advances in Treatment
The advent of combination therapies, including proton pump inhibitors (PPIs) and antibiotics, has proven highly effective in eradicating H. pylori. As a result, patients who once had recurrent ulcers now enjoy reduced risks for future complications.
What is the Main Reason for Surgical Treatment of Peptic Ulcer Nowadays?
In contemporary medical practice, the primary indication for surgical intervention in peptic ulcers is perforation. This condition is particularly prevalent due to the increased usage of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Acetylsalicylic Acid (ASA), especially among the aging population. The widespread consumption of these medications can lead to ulcer complications, necessitating surgical treatment.
Elective Surgical Indications for Peptic Ulcer
Surgeons may opt for elective surgery in cases of gastroduodenal ulcers under certain conditions, including:
- Ulcer refractory or persistent to medical treatment: When patients do not respond to standard therapies, surgical intervention may be necessary.
- Suspicion of malignancy: If cancer is suspected in or around the ulcer, surgical removal for biopsy may be warranted.
- Non-dilative stenosis: A narrowing of the gastrointestinal tract due to scarring from the ulcer could require surgical correction.
Urgent Surgical Indications for Peptic Ulcer
In urgent situations, the following conditions call for immediate surgical intervention:
- Hemorrhage not resolved endoscopically: If bleeding continues despite endoscopic treatment, surgery may be necessary.
- Drilling: This term refers to the perforation of the ulcer, requiring urgent surgical repair.
The Most Common Complication of Peptic Ulcer that Requires Surgery
While perforation is the most severe complication of peptic ulcers, hemorrhage is the most frequent. Prompt recognition and treatment of these complications are essential to improve patient outcomes.
Factors Increasing the Risk of Perforation in Peptic Ulcer
Several factors significantly raise the risk of perforation, including:
- Tobacco use: Smoking can exacerbate ulcer formation and impede healing.
- Use of NSAIDs and ASA: These medications can irritate the stomach lining, increasing the likelihood of perforation.
- Consumption of cocaine and psychostimulants: These substances can lead to gastrointestinal complications, including perforation.
Clinical Manifestations of Perforated Gastroduodenal Ulcer
A perforated gastroduodenal ulcer presents with sudden and intense epigastric pain that may radiate to the shoulders. Patients often experience nausea and vomiting, alongside signs of peritoneal irritation such as a “table abdomen.” In advanced cases, there may be indications of sepsis, necessitating immediate medical attention.
Diagnostic Tests for Suspected Ulcer Perforation
If perforation is suspected, an upright chest X-ray should be performed to check for pneumoperitoneum, an accumulation of air under the diaphragm that suggests perforation.
Surgical Treatment for Perforated Ulcer
The surgical procedure for treating a perforated ulcer involves closing the perforation, typically accompanied by omentoplasty (using the omentum to reinforce the closure) and washing the abdominal cavity. Most surgeries are now performed laparoscopically, minimizing recovery time. In cases of gastric ulcers, tissue resection may be necessary for pathological examination.
Non-Surgical Treatment for Perforated Ulcer
In select cases, non-surgical treatment may be an option for patients who are hemodynamically stable, exhibit no peritonitis, and show signs of perforation without free air. These cases are rare and should be treated with caution.
Bleeding as a Complication of Peptic Ulcer
Bleeding is a known complication present in 20-25% of peptic ulcers, making it a significant concern in clinical practice.
Most Common Cause of Upper Gastrointestinal Bleeding
Duodenal ulcers, particularly those located on the posterior surface, are the leading cause of upper gastrointestinal bleeding.
Treatment of Choice for Peptic Ulcer Bleeding
Endoscopy serves as both a diagnostic and therapeutic tool for treating peptic ulcer bleeding. In cases where endoscopic measures fail, surgical intervention becomes necessary.
Surgical Intervention for Bleeding Ulcer
Surgical intervention may be indicated if:
- Endoscopic control fails.
- Patients exhibit severe hemodynamic instability.
- More than six units of concentrated blood are required within 24 hours.
- Rebleeding occurs after initial endoscopic hemostasis.
Goal of Surgery for Ulcer Bleeding
The primary goal of surgical intervention is to halt the bleeding through methods such as suturing the bleeding vessel or resecting the ulcer if required.
Elective Surgical Treatment for Peptic Ulcer
Elective surgical treatment is considered for patients encountering complications like pyloric stenosis or those who do not respond to standard medical therapies.
Clinical Manifestations of Pyloric Stenosis
Pyloric stenosis can present with symptoms such as early satiety, bloating, nausea, vomiting, and significant weight loss or malnutrition due to impaired gastric emptying.
Surgical Options for Treating Pyloric Stenosis
Treatment options for pyloric stenosis may include:
- Pyloroplasty: A procedure to widen the pylorus.
- Gastroduodenostomy (Finney): Creating a new connection between the stomach and duodenum.
- Truncal vagotomy with antrectomy: Cutting the vagus nerve and removing the pylorus.
Surgical Indication for Refractory Ulcer
Surgical intervention is indicated if the ulcer persists despite 8-12 weeks of appropriate treatment. Elective surgery may be needed due to drug intolerance, suspected malignancy, or patient risk factors.
Conclusion
The landscape of peptic ulcer diagnosis and treatment has evolved immensely, with a notable decrease in incidence largely due to the effective management of H. pylori infections. Although surgical treatments are less common than in the past, they remain a critical component in managing complications arising from peptic ulcers. Understanding indications for surgical intervention ensures that patients receive appropriate and timely care, ultimately improving their health outcomes.