Medical Express revealed that excessive intake of fats and carbohydrates leads to obesity and associated metabolic disorders including fatty liver disease. Some people with nonalcoholic fatty liver disease develop a more aggressive form known as nonalcoholic steatohepatitis. (NASH) Where the liver is inflamed.
This can develop into advanced scarring known as cirrhosis, which can lead to liver failure and cancer, however, vitamins rich in calcium, magnesium and additional elements (derived from calcified red algae), can help stop this progression.
Preclinical study results add new evidence that a multi-mineral supplement might be a simple and effective way to reduce the long-term health consequences of nonalcoholic fatty liver disease. Minerals, derived from red marine calcified algae, are rich in calcium, magnesium and 72 other minerals and trace elements..
About 25% of people in the United States suffer from nonalcoholic fatty liver disease, which is characterized by an excess of fat stored in the liver. Some people with this disease develop a more aggressive form known as nonalcoholic steatohepatitis. (NASH) Where the liver is inflamed, this can develop into fibrosis, advanced scarring known as cirrhosis, liver failure, and cancer..
“New methods are needed because these minerals do not work for everyone,” said lead researcher Dr. Muhammad Nadim Aslam, a physician from the University of Michigan..”
“Most people who live in Western society do not adhere to the USDA’s daily intake guidelines regarding intake of calcium, magnesium, and possibly other minerals nutritionally related to these minerals,” said Isabel Harper, a university researcher at the University of Michigan. Could provide a low-cost, low-to-no-toxicity approach to mitigating the devastating consequences of nonalcoholic fatty liver disease..”
In preliminary studies, researchers fed mice a high-fat diet to induce the development of nonalcoholic fatty liver disease and NASH They studied these mice for 15 to 18 months to monitor the full spectrum of liver disease, including advanced fibrotic changes and liver cancer..
These studies revealed a significant reduction in the late-stage sequelae of NASH in animals that have been fed High fat diet Those who received a multimineral supplement compared to those who did not receive the supplement. In short-term studies lasting regarding 24 weeks, researchers identified protein changes associated with NASH and reduced tumor formation in longer studies.
Aslam emphasized, “In the long-term studies, we observed that most mice on a high-fat diet had large tumors in the liver, while mice on the same diet did not have tumors when they received mineral supplements.” These findings confirmed our findings Earlier that minerals may have the ability to reduce the final consequences of fatty liver disease.”
Because the short- and long-term studies were conducted using different types of mice, the researchers then plan to conduct both sets of studies on the same animals. This will allow them to identify early changes in the animals that may predict later consequences or be associated with protection once morest such consequences..
