Study: Cellular aging accelerates sharply between ages 40 and 60

According to scientists, this explains the sharp increase in the incidence of many age-related diseases.

“We found that the way the body works doesn’t change smoothly with age,” says Professor Michael Snyder. “Sometimes there are sharp changes in the way cells work. For example, these sharp changes in biomarkers of aging appear in the mid-40s. Another change occurs in the early 60s. This is generally normal for all biomarkers.”

The researchers reached this conclusion by following the lives of about 100 volunteers aged 25-75 years. The researchers took samples of their blood and other biological fluids over several years, during which they measured the concentration of key biomarkers associated with cell aging and tracked the change in their concentration with age.

The researchers found that the concentration of 81 percent of these indicators did not change gradually, but rather suddenly in the majority of volunteers. It appeared that the change in the proportions of these substances in the volunteers’ bodies occurred suddenly. The first change occurred at the age of 44, and the second change at the age of 60. According to scientists, the first change is related to the metabolism process, and the second is related to the immune system, kidneys, and heart.

Researchers found that these changes affect both men and women, and are the cause of many diseases of old age, including dementia and various heart diseases.

Source: TASS