2024-03-13 23:38:00
The more solid lung cancer is, the higher the possibility of lymph node metastasis.
Professor Dong-wook Yoon, Soo-hwan Choi, and Cho Joong-ho, 5-year survival rate of ground glass shade 94% vs. pure solid 71%
2024.03.14 08:38 Write a comment
Research results have been published showing that ‘solid’ lung cancer is more likely to metastasize to the lymph nodes.
The research team, including Professor Dong-wook Yoon of Cardiovascular and Thoracic Surgery at Chung-Ang University Hospital (Director Jeong-taek Kwon), Professor Soo-hwan Choi of Hanyang University Hospital, and Professor Cho Jong-ho of Samsung Seoul Hospital, recently published a research paper on hidden lymph node metastases observed in patients who underwent surgery for early-stage lung cancer in an international journal. Published in an academic journal.
The research team identified 591 patients with tumors containing ground-glass shadows among patients who underwent lung resection following being confirmed to have early lung cancer less than 2 cm without lymph node metastasis in preoperative CT and PET-CT imaging tests, and 591 patients with tumors that appeared to be pure solid. A comparative analysis was conducted on 738 patients.
As a result, there was a difference in the rate at which hidden lymph node metastases were identified depending on the shape and size of the tumor seen in the CT image.
‘Ground glass opacity’ is a phenomenon in which a part of the lung appears cloudy in a CT image, like glass made opaque by rubbing the glass surface with sandpaper. ‘Hidden lymph node metastasis’ was confirmed with a probability of approximately 2%.
The ‘pure solid’ form is a tumor in which the entire nodule is opaque and the internal lung tissue is not completely visible. The larger the size, the higher the confirmation rate of lymph node metastasis following surgery, up to 21.31%.
In addition, the 5-year disease-free survival rate for patients with pure solid form cancer was 71.2%, which was significantly lower than the 94.4% survival rate for patients with ground glass shade.
Accordingly, the research team recommended, “Even if the lung cancer is small in size, if it is a purely solid cancer, lymph node dissection must be performed during the lung resection surgery.”
Professor Yoon said, “In particular, ‘hidden lymph node metastasis’ was often identified in patients with cancer that appeared to be in pure solid form. Predicting metastasis is an important clue to prevent chemotherapy, which is inevitably accompanied by side effects.” said.
Professor Choi said, “This study is expected to help determine treatment policies for patients with pure solid lung cancer in the future.”
Meanwhile, this research paper was published in the March 2024 issue of ‘Annals of Thoracic Surgery’, a SCIE-level official international journal published by the American Society of Thoracic Surgery.
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