Side effects of the vaccine would have a direct link to the production of antibodies

2023-10-16 16:32:36

Many people have experienced various side effects following receiving the Covid-19 vaccine (or a booster). Headaches, fatigue, painful joint swelling, tremors: some patients have even reported severe effects, sometimes as much as the virus itself.

According to an American study published at the beginning of October on MedRxiv, this is however a good thing. According to researchers, the greater the side effects, the more effective the vaccine is in the patient’s body, reports National Geographic relayed by Slate.

Witness side effects

“The more symptoms people reported, the higher their antibody levels were,” summarized Aric Prather, lead author of this study which has not yet been peer-reviewed. The researcher and his team analyzed blood samples from 364 adults before the vaccine and six months following the injection to measure the level of antibodies. At the same time, participants were asked to report possible symptoms.

Result: there would be a direct link between the symptoms experienced and the level of antibodies recorded six months later. These results are in line with the statements of immunologist Drew Weissmann, co-winner of the Nobel Prize in Medicine with his colleague Katalin Karikó, for their related work on messenger RNA. “The side effects show that the vaccine works,” he said.

A painful vaccine

However, you don’t need to suffer for the vaccine to work either. “In fact, in many people who described mild or no symptoms, the formation of more than sufficient antibodies was sufficiently high,” explained Aric Prather. In another study, 98% of patients who experienced few or no side effects still had sufficient levels of antibodies.

More generally, it appears that messenger RNA vaccines are among the most painful, with side effects comparable to the shingles vaccine. The intensity of these effects remains largely a mystery to scientists. “There is still so much to learn regarding the side effects of messenger RNA vaccines,” emphasized vaccinologist Deborah Fuller.

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