2023-06-01 06:40:07
The main reason for the development of the disease has been identified.
Scientists at the University of Pittsburgh have solved a long-standing mystery surrounding the development of Alzheimer’s disease. Experts for a long time might not understand why some people with an excess of toxic amyloid proteins in the brain (associated with the disease) never develop dementia.
It turned out that the key reason for this is astrocytes, which provoke the disorder.
The results of the work are published in the journal Nature Medicine.
During the study, the authors analyzed the blood of more than a thousand cognitively healthy older people with and without amyloid accumulations. The main attention of researchers was occupied by biomarkers of astrocyte reactivity – glial fibrillary acidic protein (GFAP), as well as tau protein.
They noticed that only those patients who had amyloid plaques in combination with markers of abnormal astrocyte activation developed Alzheimer’s disease in the future. The discovery is important for the development of new therapeutic directions for the fight once morest dementia.
In addition, the inclusion of biomarkers such as GFAP in diagnostics will improve the selection of patients in whom the disease progresses at later stages.
In May 2022, researchers at the Ian and Dan Duncan Neurological Research Institute and Baylor College of Medicine used artificial intelligence to discover gender differences in the genes responsible for Alzheimer’s disease.
Some foods can speed up the aging process. Look in the gallery, what is better to exclude from your diet:
Carbonated mineral water.
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Snacks and chips.
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Bakery products of industrial production.
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Desserts high in sugar.
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Cornflakes.
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Semi-finished products.
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Sausages and processed meat products.
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Frozen industrial pizza.
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Milkshakes.
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Desserts with processed milk.
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Instant noodles.
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Juices (except freshly squeezed).
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Fruit yoghurts of industrial production.
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