2023-08-09 12:15:00
Without blood vessels, we might not live. This network, which transports blood from one organ to another and eliminates waste, is vital to us.
Blood vessel failure is the main reason why cardiovascular disease is the leading cause of death worldwide. This explains the importance of being able to replace these vessels in the event of failure.
Researchers from the Australian University explain in their report that the methods currently used to create blood vessels in medicine are slow, or require specialized and expensive equipment.
The team thus developed a blood vessel from several materials including human muscle cells.
The researchers are optimistic regarding their research: “ This approach represents a significant advance in tissue engineering, enabling fabrication of TEVGs (tissue-engineered vascular grafts) with appropriate mechanical properties that recapitulate key structural features of NBV (functional native blood vessels) cells within hours using a scalable and accessible method . TEVGs demonstrated similar mechanical properties to NBVs, which may facilitate future translation.
What is Tissue Engineering?
Tissue engineering is a set of innovations that can replace failing organs or help the functioning of certain. Artificial vessels, heart valves, stents, dental implants, hip prostheses, synthetic bone or cartilage, artificial heart, pins, drains, suture materials, portable pumps or even cell or tissue grafts, all of which make it possible to repair or to regenerate the human body are biomaterials and derived from tissue engineering.
What does tissue engineering allow?
Today, it is 3D printing that is at the heart of many innovations, as in 2022, with the case of an American suffering from microtia (malformation of the ear), having had a bioprinted ear transplanted in 3D.
In France, a team of surgeons from Toulouse achieved the feat of implanting a nasal graft made of synthetic biomaterial produced on a 3D printer. More than ten years following being treated for cancer of the nasal cavities (squamous cell carcinoma) by radiotherapy and chemotherapy, the operated woman was the first patient in the world to have benefited from this type of intervention.
Even more surprisingly, a Londoner benefited in 2021 from the first ocular implant made using a 3D printer.
For the information scientist at the American Chemical Society, Chia-Wei Hsu, 3D printing is only in its infancy, the progress to be made is still many although the results so far obtained are remarkable: “While we have seen many fascinating advances in biomedical 3D printing, in many areas the technology is still in its infancy. For example, researchers successfully bioprinted vascularized cardiac patches, but building a robust heart valve (let alone an entire organ) is still far from a reality. »
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