Researchers at the University of Eastern Finland conducted an extensive meta-analysis of dozens of publications that found that vitamin D supplements can improve symptoms in adults with depression. The article was published in the journal Critical Reviews in Food Science and Nutrition.
The new meta-analysis linking vitamin D supplementation to depression is the largest published to date. It includes the results of 41 randomized, placebo-controlled trials in different populations from around the world. The results of a meta-analysis showed that vitamin D supplementation is more effective than placebo. There was great variation in the doses of vitamin D used, but the average was 50–100 micrograms per day. The publications included in the meta-analysis did not look at the effects of sun exposure on vitamin D synthesis and also excluded patients with bipolar disorder.
The therapeutic efficacy of modern antidepressants is often insufficient, so additional ways to relieve symptoms of depression are also being sought through nutritional supplements. Cross-sectional studies have shown a correlation between depressive symptoms and vitamin D deficiency, but not a causal relationship, so the results of the analysis should be treated with caution. Moreover, previous meta-analyses of the effects of vitamin D supplementation on depression have not shown its unequivocal effectiveness.
The meta-analysis was conducted as part of an international collaboration between researchers from the University of Eastern Finland, Deakin University (Australia), Massachusetts Hospital Boston, the University of Kuopio, and the University of Helsinki.
Doctors and scientists consider the Mediterranean diet one of the healthiest. It has been scientifically proven to contain a balanced diet rich in vitamin D as well. What foods are included in this diet? Find out in the gallery:
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