2023-12-23 08:07:25
▲ Research results have shown that heavy alcohol drinking can rapidly increase the risk of alcoholic cirrhosis. (Photo = DB)
[메디컬투데이=최재백 기자] It has been shown that binge drinking can dramatically increase the risk of alcoholic cirrhosis.
Research results showing that binge drinking can rapidly increase the risk of alcohol-related liver cirrhosis were published in the academic journal ‘Nature Communications’.
Alcoholic cirrhosis was thought to be a disease related to chronic alcohol abuse, but recent studies have shown that even short-term binge drinking can cause alcoholic cirrhosis.
The research team reported that if a genetically high-risk group for alcoholic cirrhosis binge drinks, the risk of developing alcoholic cirrhosis may increase six times compared to a genetically low-risk group that drinks only a moderate amount per day.
They mentioned that binge drinking in patients with type 2 diabetes can also increase the risk of alcoholic cirrhosis, and explained that if binge drinking, genetic predisposition, and type 2 diabetes are all present, how you drink plays a more important role in the development of cirrhosis than how much you drink. did.
Binge drinking, genetic predisposition, and type 2 diabetes are risk factors that individually increase the risk of alcoholic cirrhosis. Binge drinking by drinking more than 12 units of alcohol at a specific time alone increases the risk of alcoholic cirrhosis by 3 times, and the risk of alcoholic cirrhosis in genetic high-risk groups and patients with type 2 diabetes is 4 times and 2 times higher than in healthy low-risk groups, respectively. It’s twice as high.
The research team warned that drinking too much or too quickly or until you get drunk can seriously harm liver health.
In addition, experts estimate that it is necessary to determine the exact mechanism of why drinking large amounts of alcohol so quickly that the liver cannot metabolize it, unlike alcohol that accumulates continuously over a long period of time, causes more serious liver damage in genetically high-risk groups. did.
They explained that when alcohol is consumed excessively, the liver is unable to detoxify all the alcohol consumed, and undetoxified toxins accumulate, leading to cirrhosis.
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) defines binge drinking as drinking to a blood alcohol level of 0.08% or higher. This refers to drinking more than 5 or 4 drinks within 2 hours for adult men and women, respectively.
The research team said that liver disease is one of the leading causes of premature death worldwide, and that people with a family history of liver disease or a genetic predisposition to alcoholism should pay special attention to their alcohol intake to prevent irreversible liver damage. I was careful.
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