2023-08-10 01:20:00
The stock price of MI Tech (179290) rose on the news that Jeong Yoon-gi, a senior researcher at the Korea Institute of Science and Technology (KIST) Biomaterials Research Center, Lee Joo-ro, a postdoctoral researcher at Harvard Medical School, and Park Hoon-joon, a professor at Catholic University Medical School, and Dr. Park Bong-woo, developed a new treatment for myocardial infarction. all.
KIST recently announced that a joint research team developed a treatment for myocardial infarction that regulates the immune response with fibroblast-derived nano-endoplasmic reticulum and published it in the June issue of the international journal Advanced Functional Materials.
Myocardial infarction is treated with drug therapy, percutaneous angioplasty, arterial bypass, etc., but severe patients who do not respond to these therapies are difficult to improve.
The research team developed nano-endoplasmic reticulum that has anti-inflammatory properties by inducing apoptosis of fibroblasts with improved surfaces and can be specifically delivered to macrophages at the site of myocardial infarction. When the nanovesicles were injected intravenously through rat experiments, it was confirmed that a large amount of this material was specifically introduced into macrophages as it was effectively delivered to the site of myocardial infarction.
Principal Researcher Jeong said, “This is the first study to apply nano-endoplasmic reticulum produced from apoptosis-induced cells to the treatment of myocardial infarction disease.” We plan to conduct clinical trials to verify safety.”
Meanwhile, MI Tech was established in 1991 as a flagship affiliate of Synergy Partners Group. It is a medical supplies and equipment manufacturing company that mainly produces non-vascular stents, which are implantable medical devices, and succeeded in developing non-vascular stents for the first time in Korea.
Recently, the world’s first biodegradable fiber material for digestive system stents was developed. Metal (magnesium) and polymer materials were mainly used as existing biodegradable stents. However, polymers have a weaker tube widening effect than metal materials.
The metal material has a relatively strong holding power of the stent, but has a limitation in that it melts quickly. MI Tech plans to catch both rabbits by using polymer materials, but adjusting the mixing of raw materials to control the holding power and melting speed following expansion. In addition, it is equipped with an anti-inflammatory drug release function that will reduce the inflammatory reaction caused by the stent.
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