American researchers have developed a blood test to detect Alzheimer’s disease. If validated, it could replace an expensive MRI or a painful and invasive lumbar puncture, the only techniques which today make it possible to reveal the existence of the disease.
The Alzheimer’s disease could it soon be diagnosed by a simple blood test? Researchers at the University of Pittsburgh in the United States have developed a blood test capable of accurately determining the presence of the disease in a patient.
The most common form of dementia, Alzheimer’s disease remains difficult to diagnose. To detect this neurodegenerative disease, three markers must be identified: abnormal accumulations of amyloid and Tau proteins, and neurodegeneration, or the progressive loss of neuronal cells in specific regions of the brain. Tests carried out using a cerebral MRI and/or an analysis of cerebrospinal fluid (CSF) taken by lumbar puncture in the lower back. Problem: Despite their effectiveness, brain imaging techniques are expensive and waiting times are often long, even in an emergency. Lumbar puncture can be invasive and painful, causing headaches and lower back pain.
This blood test could therefore be more accessible and above all, detect the disease earlier. “A blood test is cheaper, safer and easier to administer, and it may improve clinical confidence in the diagnosis of Alzheimer’s disease.”told the Guardian Professor Thomas Karikari, from the University of Pittsburgh in the United States, who participated in the study.
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