When President Biden assumed office in January 2021, the United States was grappling with the most severe public health crisis in over a century. The COVID-19 pandemic had upended daily life, shuttering businesses, disrupting education, and isolating communities. By the end of the first year, nearly 400,000 Americans had lost their lives to the virus, underscoring the urgency of a robust and coordinated response.
Even before his inauguration, president-elect Biden understood the gravity of the situation. He envisioned a comprehensive emergency strategy that woudl harness the collective power of the federal government, private sector innovation, and the resilience of the American people.On his first full day in office, President Biden unveiled the National Strategy for the COVID-19 Response and Pandemic Preparedness. This blueprint aimed to equip individuals with the tools and information needed to safeguard their health,reopen schools,and revitalize the economy.
The Biden-Harris Governance’s approach to combating COVID-19 was multifaceted,addressing both immediate challenges and long-term preparedness.Their efforts not only mitigated the pandemic’s impact but also established a framework for future public health crises. Below, we explore the key initiatives that defined their response.
1 – Launching the Largest Vaccination Effort in U.S.History
Table of Contents
- 1. 1 – Launching the Largest Vaccination Effort in U.S.History
- 2. 2 – Expanding Access to Testing
- 3. 3 – Building a Roadmap for Future Crises
- 4. How the Biden-Harris Administration Transformed COVID-19 Response and Recovery
- 5. Expanding Access to Diagnostic Testing
- 6. Boosting Treatment Availability
- 7. Ensuring Equity in Pandemic Response
- 8. A Legacy of Resilience
- 9. How the Biden-Harris Administration Transformed America’s COVID-19 Response
- 10. A Historic Vaccination Campaign
- 11. Expanding access to Testing
- 12. Reviving the Economy and Reducing Inequities
- 13. Reopening Schools and Restoring Normalcy
- 14. Shifting Public Perception
- 15. Ongoing Efforts to Protect Americans
- 16. Addressing Long COVID
- 17. A Global Response
- 18. How the U.S. Led Global Efforts to Combat COVID-19 and Strengthen Health Security
- 19. Revitalizing Global partnerships
- 20. Leading the Charge in Vaccine Donations
- 21. Addressing the Decline in Routine Immunizations
- 22. Innovating for Future Threats
- 23. Delivering Critical Resources
- 24. How the U.S. is Tackling Global Health Threats and Strengthening Vaccine Manufacturing
- 25. Global Vaccine Manufacturing and Technical Assistance
- 26. Managing Current Public health Threats
- 27. Avian Flu: A Growing Concern
- 28. Lessons from COVID-19: A Blueprint for Future Crises
- 29. Combating Avian Flu: A nationwide Effort to Protect Dairy Farms and Public Health
- 30. Collaborative Monitoring and Early Detection
- 31. Protecting Workers and Building Trust
- 32. Preparing for the Future
- 33. How the Biden-Harris Administration Tackled Emerging Infectious Diseases
- 34. Mpox: A Rapid and effective Response
- 35. Equitable Access and community Engagement
- 36. Global Leadership in 2024
- 37. Marburg: Preparedness and innovation
- 38. Ensuring Food Safety Amid Emerging Threats
- 39. Looking Ahead: A Safer future
- 40. Strengthening america’s Defense Against Biological threats
- 41. replenishing the Strategic National Stockpile
- 42. Expanding Disease Surveillance and Preparedness
- 43. Global Health Security and Measles Response
- 44. Building Resilience for Future Threats
- 45. How the U.S. is Strengthening Pandemic Preparedness and Public Health Infrastructure
- 46. Revolutionizing disease Surveillance
- 47. Creating a COVID-19 Variant Playbook
- 48. Enhancing Data Sharing Across Hospitals
- 49. Investing in RNA Vaccine Technologies
- 50. Strengthening the Domestic PPE Supply Chain
- 51. Transforming Biopreparedness Capabilities
- 52. Conclusion
- 53. Building a Resilient Global Health System: Innovations in Pandemic Preparedness
- 54. A New Era of global Health Financing
- 55. Investing in Innovation: mRNA Technology and Beyond
- 56. Strengthening Research and Oversight
- 57. A Global Commitment to Health Security
- 58. Strengthening Global Health security: Key Initiatives and Achievements
- 59. Enhancing Research Oversight
- 60. Global Biosafety and Biosecurity Efforts
- 61. Office of Pandemic Preparedness and Response Policy (OPPR)
- 62. Conclusion
- 63. Strengthening America’s Pandemic Preparedness: A three-Step Playbook for Future Threats
- 64. The Three-Step Framework for Crisis Response
- 65. How might the management’s investment in AI and other advanced technologies for pandemic preparedness mitigate risks while balancing the need for continued innovation in life science research?
- 66. Step 1: Investing in Cutting-Edge Research and Development
- 67. Step 2: Strengthening Global and Domestic Health Infrastructure
- 68. Step 3: Enhancing Oversight and International Collaboration
- 69. Conclusion
Central to the administration’s strategy was the rapid deployment of vaccines. Recognizing their potential to reduce hospitalizations and deaths, the Biden-Harris team collaborated with healthcare professionals, businesses, community organizations, and local leaders to prioritize vaccination efforts. This unprecedented campaign resulted in the largest free vaccination program in American history.
Over 90,000 vaccination sites were established, including mass vaccination centers capable of administering more than 125,000 doses daily. The federal government deployed over 9,000 personnel, including 5,000 active-duty troops, to support these efforts. Additionally, the launch of vaccinefinder.org provided real-time information on vaccine availability, making it easier for Americans to locate nearby sites.
Pharmacies played a pivotal role in this initiative. with most Americans living within five miles of a pharmacy, the Federal Retail Pharmacy Program (FRPP) partnered with 21 retail and long-term care pharmacies to offer vaccines at over 41,000 locations nationwide. By May 2023,more than 270 million people had received at least one dose of a COVID-19 vaccine. According to a December 2022 analysis by the Commonwealth Fund, these vaccinations saved over 3 million lives and prevented 18 million hospitalizations.
2 – Expanding Access to Testing
Testing was another cornerstone of the administration’s strategy. Early in his term, President Biden announced a $650 million investment to expand testing for schools and underserved communities, followed by an $815 million commitment to boost domestic production of testing supplies.These measures ensured a steady and reliable supply of tests,reducing dependence on international manufacturers.
The administration also partnered with private companies to develop at-home testing kits, making it easier for individuals to monitor their health without visiting a doctor’s office. Free testing sites were made available at 21,500 locations across the country, thanks to federal efforts to expand pharmacy-based testing. This widespread accessibility empowered Americans to make informed decisions about their daily activities, further curbing the virus’s spread.
3 – Building a Roadmap for Future Crises
Beyond addressing the immediate challenges of COVID-19, the Biden-Harris Administration laid the groundwork for future pandemic preparedness.Their comprehensive approach included transparent interaction, equitable resource distribution, and cross-sector collaboration. These principles are encapsulated in a three-step playbook designed to guide future administrations in responding to biological threats.
By prioritizing vaccination,expanding testing,and fostering innovation,the administration not only mitigated the impact of COVID-19 but also strengthened the nation’s resilience against future public health emergencies.Their efforts serve as a testament to the power of collective action and strategic planning in overcoming unprecedented challenges.
How the Biden-Harris Administration Transformed COVID-19 Response and Recovery
When the COVID-19 pandemic struck, it exposed deep-rooted health and social inequities across the United states. Recognizing the urgency, the Biden-Harris Administration took swift and decisive action to mitigate the crisis, focusing on equitable access to testing, treatments, and vaccines. Their efforts not only saved lives but also set a new standard for pandemic response.
Expanding Access to Diagnostic Testing
One of the Administration’s most impactful initiatives was the rapid deployment of COVID-19 diagnostic tests. By leveraging the American Rescue plan (ARP), the government allocated $10 billion to provide tests to K-12 school districts and invested nearly $6 billion to cover free testing for uninsured individuals. This funding also supported testing in correctional facilities, homeless shelters, and mental health centers.
To ensure widespread access, the Administration launched COVIDtests.gov, a platform where Americans could order free tests delivered directly to their homes via the United States postal Service. By the end of the Public Health Emergency in May 2023, over 750 million tests had been distributed to more than 85 million households. Additionally, more than 50 million tests were administered at pharmacies and community-based sites nationwide.
These efforts paid off.A study published in The Lancet public Health revealed that the widespread availability of diagnostic tests prevented an estimated 7 million hospitalizations and saved approximately 1.4 million lives.
Boosting Treatment Availability
Beyond testing, the Administration prioritized the development and distribution of COVID-19 treatments. By March 2022, 5 million antiviral treatment courses were made available to Americans. The Test-to-treat initiative, announced by President biden, streamlined access to free oral antivirals for high-risk individuals and those with limited financial means.
By April 2022, the U.S. government had purchased 20 million treatment courses—more than any other country. The Administration also doubled the number of locations where Americans could access these treatments and provided healthcare providers with the tools and education needed to prescribe them effectively.
Ensuring Equity in Pandemic Response
on his first day in office, President Biden signed an Executive Order to address the disproportionate impact of the pandemic on marginalized communities. This led to the creation of the COVID-19 health Equity Task Force, which worked to ensure that testing, treatments, and vaccines reached underserved populations.
Local partnerships played a crucial role in this effort. Businesses offered paid time off for employees to get vaccinated, while childcare providers introduced drop-in services for caregivers. Public transit systems and ride-sharing companies provided free transportation to vaccination sites, and community organizations hosted pop-up clinics in churches and civic centers.
A Legacy of Resilience
The Biden-Harris Administration’s comprehensive approach to the pandemic not only saved lives but also strengthened the nation’s public health infrastructure. By prioritizing equity, accessibility, and innovation, they demonstrated how a coordinated response can turn the tide of a global crisis.
As we reflect on these achievements, it’s clear that the lessons learned will shape future responses to public health emergencies, ensuring that no community is left behind.
How Community Health Centers Became the Backbone of COVID-19 Response:
When the COVID-19 pandemic hit, Community Health Centers emerged as the cornerstone of equitable healthcare access. These centers, frequently enough the lifeline for underserved urban and rural populations, took on a monumental role in testing, vaccination, and treatment.Millions of COVID-19 tests were administered, vaccine doses distributed, and telehealth services expanded to ensure no one was left behind. Patients also gained access to cutting-edge treatments like oral antiviral medications and monoclonal antibody therapy. Through programs like the COVID-19 Testing Supply and N95 Mask initiatives, health centers provided millions of free masks, at-home test kits, and point-of-care supplies to communities, ensuring safety without financial burden.
Empowering Local Voices to Reach High-Risk Communities:
Recognizing the power of trusted local messengers, the Administration focused on community-based organizations to drive vaccine outreach. Educational materials were translated into 14 languages, ensuring accessibility across diverse populations. These resources were distributed nationwide through faith-based groups, doctors’ offices, pharmacies, and employers. This strategy not only reached the unvaccinated but also emphasized the importance of boosters, supported pediatric vaccination efforts, and kept communities informed with critical COVID-19 updates.
investing in the Hardest-Hit Populations:
Over $785 million from the American Rescue Plan was allocated to build vaccine confidence in communities with historically low vaccination rates—including communities of color, rural areas, and low-income populations. Tribal communities were supported in spreading awareness about virus mitigation,while public health systems were strengthened to protect older adults,who faced the highest risk of infection and death. The Administration also prioritized Long COVID services and research, ensuring equitable access to at-home testing for disabled individuals and other high-risk groups.Investments were made to boost vaccine confidence and accessibility among people with disabilities, addressing the pandemic’s disproportionate impact on this community.
Revitalizing the Workforce to Serve Underserved Communities:
The Administration’s focus on workforce development ensured that underserved communities received the support they needed. By training and mobilizing healthcare professionals, these areas saw improved access to care, testing, and vaccination services. This effort not only addressed immediate pandemic needs but also laid the foundation for long-term health equity.
Getting America Back on Its feet:
The Administration’s comprehensive approach saved countless lives by ensuring access to safe tests, treatments, and vaccines. By minimizing the pandemic’s impact on employers, families could return to work and school, and the economy rebounded faster and more broadly than any other leading global economy. As one Administration statement noted, the country’s recovery was “faster and more broadly” than others, a testament to the collective effort.
Progress By the Numbers:
- By May 2023, COVID-19 deaths had declined by 95% compared to January 2021, and hospitalizations dropped nearly 91%. Unvaccinated individuals were significantly more likely to be hospitalized or die from COVID-19 compared to vaccinated people.
How the Biden-Harris Administration Transformed America’s COVID-19 Response
When the COVID-19 pandemic swept across the globe, it brought unprecedented challenges to public health, education, and the economy. The Biden-Harris Administration stepped into office during one of the most critical moments in modern history, implementing a robust and equitable response that not only saved lives but also laid the foundation for a historic recovery.
A Historic Vaccination Campaign
One of the most remarkable achievements of the Biden-Harris Administration was the execution of the largest domestic vaccination program in U.S. history. By May 2023, over 270 million Americans had received at least one dose of a COVID-19 vaccine. At its peak, the program administered more than 4 million vaccines in a single day—equivalent to 2,700 shots every minute. This monumental effort ensured that lifesaving treatments were widely accessible, with over 15 million courses of therapeutics distributed to those in need.
Expanding access to Testing
Testing played a pivotal role in curbing the spread of the virus. Through initiatives like covidtests.gov, the Administration delivered more than 921 million free COVID-19 tests to over 85 million households by January 2025. Additionally, more than 50 million diagnostic tests were administered at pharmacies and community-based sites, making testing more convenient and accessible for millions of Americans.
Reviving the Economy and Reducing Inequities
The American Rescue Plan (ARP) was a cornerstone of the Administration’s economic recovery strategy. By accelerating job growth and GDP expansion, the ARP helped the U.S. avoid a potential double-digit recession in spring 2021. According to one analysis, the plan created 4 million jobs and nearly doubled GDP growth. Importantly, the ARP also addressed systemic inequities, significantly reducing child poverty, food insecurity, and unemployment in low-income communities and communities of color.
Reopening Schools and Restoring Normalcy
Education was another critical focus. By March 2020, all public schools in the U.S. had closed to slow the virus’s spread.By November 2020, 19% of districts remained fully remote, while 45% used hybrid models and 36% returned to in-person learning. Under the Biden-Harris Administration, this shifted dramatically. By early May 2021, just three months into the new administration, only 1% of districts were fully remote, and over half of schools had resumed in-person instruction. This allowed families to return to work and students to regain a sense of normalcy.
Shifting Public Perception
The Administration’s efforts were reflected in public sentiment. In December 2020, 60% of Americans believed COVID-19 was worsening, according to Gallup polling. By June 2021, that figure had plummeted to just 3%. Similarly, the percentage of Americans worried about contracting the virus dropped from over 50% in December 2020 to less than 20% by june 2021.
Ongoing Efforts to Protect Americans
Even as the immediate crisis subsided,the Administration continued to prioritize public health. Free COVID-19 tests remain available through COVIDTests.gov, and authorities allowing pharmacists and pharmacy technicians to administer vaccines have been extended. This ensures that healthcare workers can focus on other critical tasks.Additionally, the Administration’s $5 billion investment in Project NextGen is accelerating the development of next-generation vaccines and treatments through innovative public-private partnerships.
Addressing Long COVID
Recognizing the lingering effects of COVID-19,the Administration has dedicated billions to research Long COVID.The first-ever National Research Action Plan on Long COVID was developed, alongside the creation of an Advisory Committee on Long COVID. These initiatives aim to uncover the causes of prolonged symptoms and develop effective treatments for the millions of Americans still affected.
A Global Response
The Biden-Harris Administration also played a key role in ensuring a coordinated global response to the pandemic.By sharing vaccines, treatments, and resources, the U.S. helped other nations combat the virus and recover economically. This global leadership underscored the importance of international collaboration in addressing public health crises.
In just a few years, the Biden-Harris Administration transformed America’s approach to the pandemic, delivering equitable solutions that saved lives, revived the economy, and restored hope for millions. As the nation continues to move forward, these efforts serve as a testament to the power of decisive leadership and collective action.
How the U.S. Led Global Efforts to Combat COVID-19 and Strengthen Health Security
When the COVID-19 pandemic struck, the Biden-Harris Administration recognized that a robust global response was essential not only for international recovery but also for safeguarding public health at home. From day one, President Biden prioritized global health security, re-establishing the National Security Council’s health security and biodefense team to address the crisis head-on.
Revitalizing Global partnerships
One of the first actions taken by the Biden administration was to rejoin the World Health Organization (WHO), reversing the previous administration’s decision to withdraw. This move was critical in ensuring coordinated global efforts to combat the pandemic.In early 2021, the U.S.pledged $4 billion to COVAX,a multilateral initiative aimed at accelerating vaccine development and ensuring equitable access worldwide. Over two years, the U.S. contributed more than $16 billion to global vaccination efforts, saving lives and strengthening health security.
The U.S. also hosted two Global COVID-19 Summits, rallying world leaders to mobilize $3.2 billion in commitments. These summits played a pivotal role in accelerating international response efforts and fostering collaboration among nations.
Leading the Charge in Vaccine Donations
The United States emerged as the largest donor of COVID-19 vaccines globally. It was the first nation to purchase doses exclusively for international donation and the first to negotiate reduced rates for the African Union, enabling the delivery of up to 110 million Moderna doses. Additionally, the U.S. pioneered efforts to deliver vaccines directly to humanitarian settings and conflict zones, ensuring displaced populations were not left behind.
Between May 2021 and February 2024, the Biden-Harris Administration donated nearly 700 million vaccine doses in collaboration with COVAX, Caricom, the African Vaccine Acquisition trust (AVAT), and through bilateral agreements. These donations reached over 44 countries in Sub-Saharan Africa, 31 nations in the Western Hemisphere, and 26 countries across Southern, Central, and Eastern Asia.
Addressing the Decline in Routine Immunizations
The pandemic disrupted routine childhood immunization programs worldwide, leading to a resurgence of vaccine-preventable diseases like measles and polio. In response, the U.S. pledged $1.58 billion in 2024 to support Gavi,The Vaccine Alliance,over the next five years. This funding builds on a 24-year partnership that has immunized over a billion children and saved 17 million lives.
The new commitment aims to vaccinate the next billion children within a decade,saving an estimated eight million lives. It will also expand access to vaccines for diseases like malaria and cervical cancer while enhancing emergency health preparedness. Through Gavi, the U.S. is supporting the African Vaccine Manufacturing Accelerator, a groundbreaking initiative to boost local vaccine production in Africa, ensuring faster and more equitable responses to future health crises.
Innovating for Future Threats
The U.S. is also a key supporter of the Coalition for Epidemic Preparedness Innovations (CEPI), which focuses on accelerating the development of vaccines against emerging diseases. CEPI’s achievements include the FDA approval of the world’s first Chikungunya vaccine and the advancement of vaccine candidates for Lassa,Nipah,and coronaviruses. Additionally,CEPI launched the Disease X Vaccine Library,prioritizing six high-risk viral families to prepare for future pandemics.
Delivering Critical Resources
Beyond vaccines, the U.S. government provided life-saving resources such as oxygen, treatments, personal protective equipment (PPE), and other essential supplies to countries in need. These efforts underscored the U.S. commitment to global health security and its role as a leader in pandemic response.
As the world continues to recover from the COVID-19 pandemic, the United States remains at the forefront of efforts to build a healthier, more resilient global community.By investing in vaccines, strengthening health systems, and fostering international collaboration, the U.S. is helping to ensure that future health crises can be met with swift and effective action.
How the U.S. is Tackling Global Health Threats and Strengthening Vaccine Manufacturing
In the face of evolving public health challenges, the United States has emerged as a global leader in combating infectious diseases and fostering innovation in vaccine production.From addressing the COVID-19 pandemic to tackling emerging threats like avian flu, the Biden-harris Administration has implemented robust strategies to protect both human and animal health. Here’s a closer look at how the U.S. is making a difference.
Global Vaccine Manufacturing and Technical Assistance
One of the most meaningful contributions of the U.S. has been its efforts to enhance global vaccine manufacturing capabilities. Recognizing the importance of equitable access to vaccines, the U.S. International Development finance Corporation (DFC) provided a $3.3 million technical assistance grant and a follow-on $15 million loan to the Institute Pasteur de Dakar (IPD) in Senegal. This funding aims to expand flexible vaccine manufacturing capacity, enabling the production of both routine and outbreak vaccines. IPD also received support from other U.S. government agencies in areas such as regulatory strengthening, workforce training, and research and development.
This initiative is part of a broader strategy to foster innovation and self-reliance in vaccine production, notably in Africa. By investing in local manufacturing, the U.S. is helping to create a more resilient global health infrastructure capable of responding to future pandemics.
Managing Current Public health Threats
The tools and strategies developed during the COVID-19 pandemic are now being applied to a range of biological threats,including avian flu,Marburg virus,Ebola,mpox,and emerging COVID-19 variants. For instance, the National Wastewater Surveillance System has proven invaluable in detecting avian flu in the environment, often before human or animal cases are confirmed. Similarly, the Traveler-based Genomic Surveillance program has been instrumental in identifying new COVID-19 variants up to six weeks before they spread widely.
Hospital data reporting systems also play a critical role in monitoring respiratory illnesses like COVID-19, flu, and RSV, providing granular insights into which healthcare facilities may face strain during peak seasons.
Avian Flu: A Growing Concern
In late March 2024, avian flu, or Influenza A(H5N1), was detected in U.S. dairy cattle for the first time. While the virus has been present in birds for decades, its spread to mammals raised alarms. The Biden-Harris Administration responded swiftly, with interagency coordination groups convening within 24 hours of the first confirmed case. These groups have been working closely with state and local officials, as well as industry partners, to monitor and contain the virus.
Key priorities include:
- Monitoring and Stopping Transmission: Enhanced surveillance and rapid response measures are being implemented to prevent further spread.
- Protecting Animal Health: Efforts are underway to ensure the safety of livestock and prevent disruptions to the food supply.
- Safeguarding Farmers and Farmworkers: programs are in place to support the livelihoods of those most affected by the outbreak.
Since 2022,the Biden-Harris Administration has allocated nearly $2.8 billion to mitigate the risks of avian flu in poultry, underscoring its commitment to protecting both public health and agricultural industries.
Lessons from COVID-19: A Blueprint for Future Crises
The COVID-19 pandemic served as a wake-up call, highlighting the need for proactive measures to address global health threats. The U.S. has taken these lessons to heart, leveraging advanced surveillance systems, fostering international collaboration, and investing in local manufacturing capabilities. These efforts not only strengthen the global response to current threats but also lay the groundwork for a more resilient future.
As the world continues to grapple with emerging health challenges, the U.S. remains at the forefront, demonstrating that innovation, collaboration, and decisive action can make a tangible difference in safeguarding public health.
Combating Avian Flu: A nationwide Effort to Protect Dairy Farms and Public Health
In April 2024, the U.S. Department of Agriculture (USDA) took decisive action to curb the spread of avian flu among dairy cattle. A federal order was issued, mandating testing for all lactating dairy cows moving across state lines.This move was part of a broader strategy to safeguard the nation’s dairy supply and prevent the virus from spreading further. Alongside the mandatory testing, the USDA introduced a voluntary program encouraging states and farmers to test their herds, implement biosecurity measures, and take advantage of incentives designed to support these efforts.
By the close of 2024, the USDA and its partner laboratories had conducted over 110,000 tests on dairy cattle. Additionally, more than 1,000 staff members were deployed to assist with on-the-ground response and traceback efforts, including 221 personnel actively working in the field.In October 2024,the USDA launched a nationwide milk testing initiative, requiring states to monitor and respond to the presence of the virus in dairy operations. Today, 28 states, representing nearly two-thirds of America’s dairy production, have joined the program. The remaining states are working to establish the necessary infrastructure to participate.
Collaborative Monitoring and Early Detection
The Centers for Disease Control and Prevention (CDC) has been at the forefront of tracking the virus through a collaborative effort involving state, local, and territorial health departments, as well as public health and clinical laboratories, clinics, and emergency departments. These systems monitor case reporting, laboratory results, emergency department visits, hospitalizations, and even wastewater to detect early signs of the virus. These measures, developed in response to the COVID-19 pandemic, provide critical insights into where the virus is spreading and whether it is causing severe illness.
When human cases of avian flu have been reported, the CDC has swiftly engaged with state and local health officials, offering technical support and deploying experts to assist with public health investigations. This proactive approach ensures that any outbreaks are contained quickly and effectively.
Protecting Workers and Building Trust
Learning from the challenges faced during the early days of the COVID-19 pandemic, the federal government has prioritized replenishing the Strategic National Stockpile. This ensures that the country is equipped with essential supplies like personal protective equipment (PPE),antivirals,tests,and vaccines to respond to health emergencies. To date, the Department of Health and human Services (HHS) has delivered nearly 4 million pieces of PPE and thousands of antiviral treatments to protect workers in affected areas.
The USDA has also implemented a reimbursement program for farmers who purchase PPE for their workers. Additionally, workers with known exposure to the virus are promptly offered post-exposure prophylaxis with Tamiflu. To build trust within impacted communities,the USDA and CDC have invested $5 million in educational campaigns and testing initiatives for farmworkers. Over 100 federal workers have been deployed to the field to support these efforts and ensure the safety of those on the front lines.
Preparing for the Future
While the focus remains on protecting workers and containing the current outbreak, federal agencies are also preparing for potential future scenarios. The CDC and the National institutes of Health (NIH) are closely monitoring the virus for any genetic changes that could make it more adaptable to humans. This vigilance ensures that the U.S. is ready to respond swiftly and effectively to any new developments.
As the nation continues to combat avian flu, the coordinated efforts of federal agencies, state governments, and local communities highlight the importance of preparedness, collaboration, and trust. By learning from past experiences and investing in robust systems, the U.S. is better equipped to protect both its agricultural industry and public health.
How the Biden-Harris Administration Tackled Emerging Infectious Diseases
Since 2021,the Biden-Harris Administration has demonstrated a proactive approach to addressing infectious disease threats,including mpox and Marburg. by leveraging existing medical countermeasures and investing in innovative solutions, the administration has been able to respond swiftly to outbreaks both domestically and globally. Here’s a closer look at their efforts and achievements.
Mpox: A Rapid and effective Response
In early 2022, the world faced an outbreak of clade II mpox, previously known as monkeypox. The virus spread rapidly across the globe, including within the United States. By May 2022, the first U.S. case was identified,prompting immediate action. The administration deployed tens of thousands of FDA-approved vaccine doses and hundreds of investigational therapeutics from the Strategic National Stockpile to curb the spread and treat affected individuals.
testing capacity was also scaled up significantly, from 6,000 to 80,000 tests per week. By October 2022, over one million doses of the JYNNEOS vaccine had been administered to high-risk individuals, and more than 40,000 treatment courses were distributed nationwide. These efforts led to a 90% reduction in domestic mpox cases. Today, the mpox vaccine is widely available at health departments and pharmacies, ensuring continued protection against both clades of the virus.
Equitable Access and community Engagement
During the 2022 response, the Biden-Harris Administration established the White House National Monkeypox Response Team. Collaborating with community-based organizations and civil society partners,the team worked to ensure equitable access to vaccines,therapeutics,and testing. Trusted community messengers played a crucial role in reaching vulnerable populations.
one of the standout initiatives was the creation of “pop-up” vaccination sites at events frequented by at-risk individuals. These sites not only provided vaccines but also educated attendees about mpox, empowering them to make informed decisions about their health.
Global Leadership in 2024
When a new clade of mpox emerged internationally in 2024, the administration was ready to act. within weeks of the World Health Organization declaring a public health emergency, President Biden announced a $500 million commitment to support African countries in combating the outbreak.This included a pledge to donate up to one million doses of mpox vaccines. As of now, two-thirds of the funding has been delivered, and all one million vaccine doses are available for distribution to countries in need.
Marburg: Preparedness and innovation
The administration’s response to Marburg, another deadly infectious disease, highlights the importance of preparedness. From day one, experimental vaccines and therapeutics were ready for deployment, thanks to prior U.S. investments. These measures allowed for rapid testing and regulatory approval, ensuring that new countermeasures could be implemented swiftly.
Ensuring Food Safety Amid Emerging Threats
Beyond infectious diseases, the administration has also prioritized the safety of the food supply. In response to concerns about new pathogens, the USDA and FDA conducted extensive testing on retail dairy samples and confirmed that pasteurization effectively inactivates harmful viruses. Similar research validated that cooking beef to proper temperatures ensures safety. Ongoing surveillance programs, including sampling muscle tissue from culled cattle, further reinforce consumer confidence in the safety of pasteurized milk, cooked meat, and eggs.
Looking Ahead: A Safer future
Most biological threats originate outside the United States, making global preparedness essential for national security. The Biden-Harris Administration’s investments in vaccines, therapeutics, and international partnerships underscore a commitment to preventing, detecting, and responding to emerging threats. By fostering collaboration and innovation, the administration is paving the way for a safer, healthier future for all.
Strengthening america’s Defense Against Biological threats
In an era where global health security is more critical than ever, the Biden-Harris administration has taken significant steps to fortify the nation’s defenses against biological threats.From bolstering the strategic National Stockpile to enhancing disease surveillance, these efforts aim to protect Americans from current and future public health emergencies.
replenishing the Strategic National Stockpile
Established in 1999, the Strategic National Stockpile (SNS) serves as a vital resource for emergency health security. Its mission is to safeguard the United States against bioterrorism, pandemics, and other public health crises.The SNS houses essential vaccines, therapeutics, and medical supplies—many of which are unavailable commercially—making it a lifeline during emergencies.
Under the Biden-Harris Administration, the SNS has seen a 25% budget increase, enabling the acquisition of more critical supplies. This expansion has been instrumental in addressing the COVID-19 pandemic, during which the SNS distributed over 27,000 tons of medical resources nationwide.Early in the pandemic,nearly 72 million items of personal protective equipment (PPE) and all Federal Medical Stations were deployed to support overwhelmed healthcare systems.
As 2021,the SNS has significantly increased its stockpiles,now holding 70 times more N95 respirators,34 times more gloves,50 times more isolation gowns,and 10 times more ventilators than before the pandemic. In 2022, the SNS made history by distributing nearly 300 million N95 masks to pharmacies and community health centers at no cost—marking the largest PPE deployment in U.S. history.
Expanding Disease Surveillance and Preparedness
The COVID-19 pandemic exposed gaps in the nation’s disease surveillance systems. To address this,the Biden-Harris Administration has prioritized modernizing data infrastructure and expanding monitoring capabilities. Enhanced surveillance systems now provide early warnings of disease outbreaks, such as mpox, through innovative methods like wastewater testing.
Domestically, efforts have focused on increasing awareness of mpox risks, updating prevention and treatment guidelines, and improving testing capabilities. The U.S. can now detect and differentiate between two mpox clades, ensuring a more targeted response to potential outbreaks.
Global Health Security and Measles Response
Beyond domestic efforts, the U.S.has collaborated with over 50 countries to strengthen global health security. These partnerships aim to prevent outbreaks at their source, protecting both international and national interests.
At home, declining measles vaccination rates have led to localized outbreaks. The administration has responded by deploying experts and distributing additional vaccine doses to affected areas. Measles vaccination remains a cornerstone of public health, with 93-95% coverage required to maintain herd immunity. As the administration emphasizes, “An unvaccinated individual exposed to the virus has a 90% chance of developing disease—therefore vaccination is critical to this response.”
Building Resilience for Future Threats
The Biden-Harris Administration’s initiatives extend beyond immediate crises, focusing on long-term preparedness. By replenishing the SNS, modernizing surveillance systems, and fostering global partnerships, the U.S. is better equipped to face emerging biological threats. These efforts underscore the importance of proactive measures in safeguarding public health and national security.
As the world continues to grapple with infectious diseases,the lessons learned from recent outbreaks will shape a more resilient future. The administration’s commitment to innovation and collaboration ensures that America remains prepared for whatever challenges lie ahead.
How the U.S. is Strengthening Pandemic Preparedness and Public Health Infrastructure
In the wake of the COVID-19 pandemic, the united States has taken significant steps to bolster its public health infrastructure, enhance disease surveillance, and prepare for future health crises. From expanding genomic sequencing capabilities to investing in cutting-edge vaccine technologies, these efforts aim to create a more resilient and responsive healthcare system. Here’s a closer look at the key initiatives shaping the nation’s pandemic preparedness.
Revolutionizing disease Surveillance
One of the most critical lessons from the pandemic was the need for faster, more accurate disease tracking. To address this, the U.S. has dramatically expanded its surveillance capabilities:
- Electronic Case Reporting: The number of healthcare facilities providing automated, near real-time electronic case reports to public health officials has skyrocketed from fewer than 200 in 2020 to over 48,000 in 2024. This system enables quicker identification of outbreaks and more effective responses.
- Wastewater Surveillance: A National Wastewater Surveillance System now monitors over 1,500 sites across the country, covering more than 150 million people. This innovative approach provides early warnings of viral spread, even before symptoms appear in communities.
- Genomic Sequencing: The U.S. has significantly scaled up its ability to detect new pathogens and variants. By the end of 2022, 68 public health laboratories had advanced molecular detection capabilities, up from just 23 at the start of the pandemic.The average turnaround time for genome sequencing has dropped from 96 to 40 days, with some labs achieving results in under two days.
Creating a COVID-19 Variant Playbook
To stay ahead of emerging threats, the U.S. developed a COVID-19 Variant Playbook. This comprehensive guide helps public health officials quickly assess the severity and transmissibility of new variants. It also accelerates the evaluation of vaccines, treatments, and diagnostic tests to ensure they remain effective against evolving strains.
Enhancing Data Sharing Across Hospitals
Collaboration between the CDC, the Centers for Medicare and Medicaid Services, and industry stakeholders has led to a major breakthrough in data sharing. Today, over 80% of U.S. hospitals share critical information on emergency department visits and hospital admissions. This real-time data exchange is vital for tracking disease trends and allocating resources effectively.
Investing in RNA Vaccine Technologies
With over $400 million in investments, the U.S. is advancing RNA vaccine technologies to combat future pandemics. Partnering with multiple companies, the Department of Health and Human Services (HHS) is exploring innovative solutions, such as needle-free vaccines, simplified storage requirements, and new administration methods. These advancements aim to create a faster, more sustainable response to emerging health threats.
Strengthening the Domestic PPE Supply Chain
To reduce reliance on foreign manufacturers, President Biden signed the “Make PPE in America Act” in 2021. This law requires federal agencies to issue long-term contracts for personal protective equipment (PPE) made exclusively from U.S.-grown or produced materials. By leveraging the federal government’s purchasing power, the act aims to boost domestic manufacturing, support competition, and ensure a steady supply of essential PPE.
Transforming Biopreparedness Capabilities
In 2022, President biden signed national Security Memorandum 15, which outlines a comprehensive strategy to counter biological threats and enhance global health security. The accompanying National Biodefense Strategy and Implementation Plan envisions “a world free from catastrophic biological incidents.” This initiative focuses on stopping outbreaks at their source, improving early detection, and strengthening international collaboration to prevent future pandemics.
Conclusion
the U.S. has made remarkable strides in pandemic preparedness, from modernizing disease surveillance to investing in next-generation vaccines and strengthening domestic supply chains. These efforts not only address the challenges posed by COVID-19 but also lay the groundwork for a more resilient and proactive public health system. As the nation continues to innovate and collaborate, the goal of preventing future catastrophic health crises becomes increasingly attainable.
Building a Resilient Global Health System: Innovations in Pandemic Preparedness
In an era where biological threats are becoming more frequent and complex, the need for a robust global health security framework has never been more urgent. The COVID-19 pandemic exposed critical gaps in the world’s ability to respond to health emergencies, prompting a reevaluation of how nations prepare for and finance pandemic prevention. The United States, under the Biden-Harris Administration, has taken significant steps to transform global health financing and strengthen preparedness efforts, ensuring a more sustainable and equitable approach to tackling future crises.
A New Era of global Health Financing
One of the most groundbreaking initiatives in recent years is the establishment of the Pandemic Fund in 2022. This multilateral financing facility, the first of its kind, is dedicated exclusively to supporting pandemic preparedness in low- and middle-income countries.In its first two years, the fund awarded $885 million in grants, which catalyzed an additional $6 billion in investments. These funds have supported 75 countries across six regions, helping them build the infrastructure needed to detect, prevent, and respond to health emergencies.
Beyond the Pandemic Fund, the U.S. has been instrumental in evolving Multilateral Development Banks (MDBs) to better address global challenges, including pandemics. The Biden-Harris Administration has also championed the International Monetary Fund Resilience and Sustainability Trust, which aims to provide long-term, affordable financing to vulnerable nations facing health emergencies and other systemic challenges.
During the COVID-19 pandemic, many countries struggled to secure the liquidity needed to procure essential medical countermeasures (MCMs). to address this, the U.S. Development Finance Corporation spearheaded the G7 Surge Financing Initiative. This collaborative effort, involving G7 development finance institutions, the European Investment Bank, and global health stakeholders, has developed innovative financing tools to accelerate access to MCMs during emergencies.
Investing in Innovation: mRNA Technology and Beyond
While the world will always face new biological threats, investing in countermeasures for known risks is a cornerstone of preparedness. The U.S. government’s early investment in mRNA technology proved pivotal during the COVID-19 pandemic. These investments not only saved millions of lives but also laid the groundwork for future advancements. The mRNA vaccine platform, for instance, can now be adapted to address other diseases and potential pandemics.
Innovation doesn’t stop at vaccines. The Department of Defense and National Laboratories are leveraging Artificial Intelligence to accelerate the development of medical countermeasures. This cutting-edge approach is part of a broader, whole-of-government strategy to enhance capabilities in early warning systems, diagnostics, therapeutics, and personal protective equipment (PPE).
Strengthening Research and Oversight
The success of COVID-19 vaccines and therapeutics was the result of decades of foundational research. Recognizing the ever-evolving nature of viruses and bacteria, the Biden-harris Administration unveiled the American Pandemic Preparedness Plan in 2021.This enterprising blueprint outlines a five-to-ten-year vision for developing biodefense capabilities, including the ability to create new vaccines within 100 days and repurpose therapeutics within 90 days.
To support this vision, the U.S. continues to invest over $7 billion annually in research aimed at combating infectious diseases like tuberculosis and HIV. These investments are critical not only for addressing current health challenges but also for building the scientific foundation needed to tackle future threats.
A Global Commitment to Health Security
The U.S. has also taken concrete steps to strengthen global health security. Through its Global Health Security Strategy, the administration has committed to supporting over 100 countries in building their capacity to prevent, detect, and respond to biological threats. This includes direct support for 50 countries and leveraging financial and diplomatic resources to assist an additional 50 nations.
As the world becomes increasingly interconnected, the importance of a coordinated, global response to health emergencies cannot be overstated. By transforming financing institutions, investing in cutting-edge research, and fostering international collaboration, the U.S.is helping to build a more resilient global health system—one that is better equipped to face the challenges of tomorrow.
Strengthening Global Health security: Key Initiatives and Achievements
In an era where global health threats are increasingly complex, the Biden-Harris Administration has prioritized strengthening biosafety, biosecurity, and pandemic preparedness. These efforts aim to safeguard the nation against future biological risks while fostering international collaboration to address shared challenges. From enhancing research oversight to expanding global biosurveillance, the Administration’s initiatives are shaping a safer, more resilient world.
Enhancing Research Oversight
In 2024, the Administration introduced updated policies to improve oversight of life science research. These revisions, building on standards established in 2012, aim to mitigate risks such as accidental outbreaks or purposeful misuse of research. By balancing safety with innovation, these measures ensure that critical, life-saving research continues without compromising public health.
Global Biosafety and Biosecurity Efforts
as technology evolves and biosurveillance capabilities expand, so do the risks of accidental or intentional biological incidents. The Biden-Harris Administration has taken proactive steps to address these challenges, emphasizing the importance of global biosafety and biosecurity practices. These efforts include:
- Minimizing laboratory accidents and preventing misuse of biological materials.
- Promoting responsible research and innovation.
- Strengthening international partnerships to enhance biosafety standards.
One notable achievement is the inclusion of biosafety and biosecurity in the Pandemic Fund grants. For instance, the Caribbean Public Health Agency’s Train-the-Trainer Workshop on the Safe Transportation of Infectious Substances has certified trainers who now serve as national advisors, improving biosafety protocols across the region.
Additionally, the Administration’s global health security partnerships have yielded significant results. According to the final global health security report, partner countries supported by the U.S. Government demonstrated measurable improvements in biosafety and biosecurity capacity between 2018 and 2023. The Administration also backed the 2024 World Health Assembly resolution on Strengthening Laboratory Biological Risk Management, further advancing global biosafety standards.
Office of Pandemic Preparedness and Response Policy (OPPR)
the OPPR has played a pivotal role in coordinating pandemic response efforts, drawing lessons from the COVID-19 crisis to inform future strategies. By collaborating with federal, state, and local health agencies, and also private sector and academic stakeholders, the OPPR has achieved several milestones:
- Resolving supply chain issues for a new immunization, reducing infant hospitalizations by over 80%.
- Partnering with international leaders to address medication supply chain challenges in the U.S. and allied nations.
- Improving vaccination rates in long-term care facilities through targeted initiatives.
- Identifying and mitigating constraints to national preparedness for future biological events.
- Developing strategies to sustain outreach to historically underserved communities, ensuring equitable access to healthcare.
Conclusion
The Biden-Harris Administration’s comprehensive approach to global health security has yielded tangible results, from reducing the impact of COVID-19 to strengthening international biosafety standards. By investing in research oversight, biosurveillance, and pandemic preparedness, the administration is building a foundation for a safer, healthier future. As the world continues to face evolving biological threats, these efforts underscore the importance of collaboration, innovation, and proactive planning.
Strengthening America’s Pandemic Preparedness: A three-Step Playbook for Future Threats
As the world continues to navigate the aftermath of the COVID-19 pandemic, life has largely returned to normal. Schools are bustling, the economy is thriving, and families are enjoying their pre-pandemic routines. However, the emergence of new viruses and biological threats has kept the Biden-Harris Administration on high alert. Through strategic investments in research, the largest vaccination program in U.S. history, enhanced surveillance systems, and the replenishment of the Strategic National Stockpile, the administration has significantly bolstered the nation’s ability to respond to health crises.
To ensure future administrations are equally prepared, the Biden-Harris team has developed a comprehensive three-step playbook. This nearly 300-page guide outlines how to swiftly and effectively address biological threats, whether they arise naturally, accidentally, or deliberately. The playbook is designed to equip leaders with the tools needed to act decisively from day one of any crisis.
The Three-Step Framework for Crisis Response
- Step 1: Immediate Assessment – Within 24 hours of identifying a serious biological threat, the national Security Council (NSC) convenes relevant departments and agencies for a Biological Incident Notification and Assessment (BINA). This step ensures a rapid evaluation of the threat’s scope and potential impact.
- Step 2: Coordinated Action – If the threat poses a significant risk to the U.S., departments and agencies establish an Incident Response Coordination Structure (IRCS) within 24-48 hours. This structure, with pre-persistent leadership and support roles, ensures a unified and efficient response.
- Step 3: Operational Response – Departments and agencies then implement a rapid and effective response, guided by the IRCS and white House leadership. the playbook includes detailed operational annexes to address common scenarios that arise during biological incidents, ensuring preparedness for a wide range of challenges.
This three-step framework has been rigorously tested under the Biden-Harris Administration, including in recent weeks. All departments and agencies have received finalized versions of the playbook,and copies will be handed over to the incoming administration to guarantee readiness from the outset of any crisis.
“The playbook includes detailed operational annexes to address many scenarios that commonly arise during biological incident responses.”
By prioritizing preparedness and proactive measures, the Biden-Harris Administration has set a new standard for pandemic response. This playbook not only reflects lessons learned from past challenges but also serves as a roadmap for safeguarding the American people against future threats.
As we look ahead, the importance of such strategic planning cannot be overstated. With this playbook in place, the U.S. is better equipped than ever to face biological threats head-on, ensuring the safety and well-being of its citizens for years to come.
How might the management’s investment in AI and other advanced technologies for pandemic preparedness mitigate risks while balancing the need for continued innovation in life science research?
Tration vigilant. Recognizing the importance of being prepared for future pandemics, the administration has developed a three-step playbook to strengthen America’s pandemic preparedness and ensure a swift, effective response to future threats.
Step 1: Investing in Cutting-Edge Research and Development
The frist step in the playbook is to accelerate innovation in medical countermeasures (MCMs). The COVID-19 pandemic demonstrated the critical role of rapid vaccine development, notably through mRNA technology. The U.S. goverment’s early investments in mRNA platforms not only saved millions of lives but also paved the way for future advancements. This technology can now be adapted to address other diseases, such as influenza, HIV, and even cancer.
Beyond vaccines, the administration is leveraging Artificial Intelligence (AI) and other advanced technologies to expedite the development of diagnostics, therapeutics, and personal protective equipment (PPE). The Department of Defence and National Laboratories are at the forefront of these efforts, using AI to identify potential threats, optimize drug revelation, and enhance early warning systems.
Step 2: Strengthening Global and Domestic Health Infrastructure
The second step focuses on building resilient health systems both domestically and globally. the Biden-Harris Administration has committed to supporting over 100 countries through its Global Health Security Strategy, helping them strengthen their capacity to prevent, detect, and respond to biological threats. This includes direct support for 50 countries and leveraging financial and diplomatic resources to assist an additional 50 nations.
Domestically,the administration is working to modernize public health infrastructure,ensuring that federal,state,and local agencies are better equipped to handle future crises. This includes improving supply chain resilience, enhancing data-sharing capabilities, and expanding access to healthcare in underserved communities. The Office of Pandemic Preparedness and Response Policy (OPPR) has been instrumental in coordinating these efforts, addressing supply chain challenges, and improving vaccination rates in long-term care facilities.
Step 3: Enhancing Oversight and International Collaboration
The third step involves strengthening research oversight and fostering international collaboration. In 2024, the administration introduced updated policies to improve the oversight of life science research, balancing safety with innovation. These measures aim to mitigate risks such as accidental outbreaks or the misuse of biological materials, ensuring that critical research continues without compromising public health.
Internationally, the U.S. has played a leading role in advancing global biosafety and biosecurity standards. This includes supporting initiatives like the Pandemic Fund, which funds projects such as the Caribbean Public Health Agency’s Train-the-Trainer Workshop on the Safe Transportation of Infectious Substances. Additionally, the administration backed the 2024 World Health Assembly resolution on Strengthening Laboratory Biological Risk management, further promoting global biosafety standards.
Conclusion
The Biden-Harris administration’s three-step playbook for pandemic preparedness reflects a proactive, thorough approach to addressing future biological threats. By investing in cutting-edge research,strengthening health infrastructure,and enhancing oversight and international collaboration,the U.S. is building a more resilient global health system. As the world continues to face evolving challenges, these efforts underscore the importance of innovation, collaboration, and preparedness in safeguarding public health and ensuring a safer, healthier future for all.