2023-10-25 15:09:56
The University Hospital of Liège and the 17 other Belgian hospitals followed 475 patients during the Covid-19 pandemic, between October 2020 and March 2022. A group of 237 people received coronavirus convalescent plasma and the other 238 received treatment standards.
Mortality reduced by 10%
According to the study, on the 28th day of treatment, mortality was reduced by 10% among patients who received convalescent plasma a maximum of five days following endotracheal intubation. In this group, 35% of patients died, while this rate increased to 45% in the group of patients who received standard care.
“The effect on reducing mortality is observed more particularly in patients to whom convalescent plasma was administered during the first 48 hours following artificial respiratory assistance,” explains Dr. Benoît Misset, head of the respiratory service. intensive care unit of Liège University Hospital and head of the study.
While various medical trials have been carried out around convalescent plasma during the Covid-19 pandemic, this is the first specifically targeting the effects on patients in acute respiratory distress requiring artificial respiratory assistance.
“This study confirms the interest in convalescent plasma for passive immunization once morest the most serious forms of Covid-19, but also once morest possible future more pathogenic variants and possibly in the case of future pandemics,” concludes Dr. Missett.
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