red mani molecule Is one of the innovation news that received a lot of attention at the end of last year When the research came out that It is a breakthrough in anti-aging science developed by Thai people.
red mani molecule being tested in the lab by injecting Mani Daeng into the abdomen of the experimental rats The results showed that red manee molecule can create DNA cleavage. The aging cells return to their shape and function normally. and is strong and nimble as a young rat It’s like going back to the age of a young mouse once more. Also, burns in lab rats healed faster. Belly fat was reduced. Importantly, the experimental old rats had better memory and learning.
for the progress of the project It is currently in testing with monkeys. And believe that within the 2nd-3rd quarter of this year there will be a test in humans. before preparing for the production process of Manee Daeng Molecules for the society If successful, it will be considered an important step in the Thai scientific community.
In this regard, red manee molecule enhances DNA joints. remove DNA lesions can correct cell aging This experiment did not destroy aging cells. But it is the replacement of aging cells back to normal functioning cells. It was also found that the brains of the old rats that received red mani improved. The experiment also showed that diseases found in senescent cells, such as senescence associated proteins, visceral fat and liver fibrosis, were reduced, while DNA cleavages were reduced. (Youth-DNA-GAP) increased, which means that the cells are younger. In addition, Maneedaeng experiments with rats with burns and rats with diabetic ulcers. The result was satisfactory, that is, the wound healed quickly and made the pork soft and firm.
Researching red manee molecule back to aging Anti-aging cells at the cellular level
The development and research of red manee molecule or RED-GEMs is a collaboration of PTT Public Company Limited, Innobic (Asia) and Chulalongkorn University by Prof. Dr. Apiwat Muti, M.D. Rangkun revealed that it was the first time in the world. From discovering the upstream mechanism of aging to development Red gem molecules or RED-GEMs (REjuvenating DNA by GEnomic Stability Molecules). (youth-DNA-gap) is in the region of DNA methylation, which is the source of Manee Daeng molecules. Which plays a role in helping to protect DNA and prevent aging in DNA
However, as people age DNA cleavage is reduced. causing tension across the strands of DNA DNA cannot rotate normally. and is easily destroyed So we found more lesions in the DNA of aging cells. This DNA lesion signals cells to stop dividing normally and enter aging. It can also lead to mutations and cancer. Red gem molecules are genes that act as scissors to create DNA cleavage. Cells receiving red mani have stronger DNA. and make the deteriorated cells come back better
“From discovery to research and development. Until entering the test in animals, namely rats, pigs and monkeys, which were tested on old rats with diabetic wounds and burns, it was found that old rats became stronger and more active. Both the functioning of the brain, liver and kidneys in the abdominal fat and fibrosis in the liver were also reduced. diabetic wound burn wound healed There were no side effects. In addition, the research team also tested it in newborn pigs. And testing the meat quality when weighing 100 kilograms, it was found that the texture was softer and firmer. Currently, the project has been tested in macaques. and rats with Alzheimer’s dementia, Parkinson’s disease, and pulmonary fibrosis. Maneedaeng has now been tested on macaques for 3 doses over a period of 3 weeks, compared to the planned 8 doses in 8 weeks. All macaques are safe. And there are no side effects, ”said Prof. Dr. Apiwat.
The importance of innovation from red mani molecule
Dr. Buranin Rattanasombat said that the company is committed to creating a business ecosystem in life sciences. to promote good quality of life and create public health security In addition to investing in drugs medical equipment and nutraceuticals We also have a goal to accelerate innovation development of Thai people to be comparable to international standards. through cooperation with networks Both researchers and universities to extend research into commercialization This is challenging and requires collaboration. both research in the laboratory
clinical research Preparation of production at the industrial level, marketing, registration and intellectual property To create research value for the Thai economy, Innobic (Asia) will support knowledge in project management. commercial marketing along with skilled personnel as well as a strong network of partners in order for the project to achieve its goals both in terms of results and duration
Maneedaeng can be considered an interesting discovery. can be extended in rehabilitation and prevention with the application of knowledge in biology, especially genetics support the country’s strategy who want to be a comprehensive medical center and develop a sustainable health promotion industry or Wellness
Prof. Dr. Bundhit Eua-arporn revealed that Chulalongkorn University Being an educational institute that pushes for sustainable innovation development Be beneficial to society (Real-world Impact Innovation) as well as aiming to use the potential of the university to respond and serve society. with creativity and instilling knowledge to create solutions to social problems Keep up with the changes and competition to become a national university that is world-class sustainable. In addition, Chulalongkorn University has transformed into a university that emphasizes innovation and social creation. Through the communication of Chula’s new slogan “Innovations for Society”, it emphasizes its position to develop innovations to meet society’s needs. Create a better society in every aspect, whether it is health. well being to the promotion of important knowledge that will drive the society forward together
Mr. Atthaphon Rerkpiboon stated that Thailand has fully stepped into an aging society. This will have an impact on public health budget expenditures. as well as driving and developing the country’s economy significantly The Company is aware of the situation that will occur. therefore aiming to create a New S-Curve business to be an important force in driving the country and taking part in leading the country to move forward with strength This is in line with the organization’s vision, Powering Life with Future Energy and Beyond, which aims to create value for society. Enhance the quality of life of Thai people Maneedaeng Project It is considered one of the achievements of commendable Thai researchers. and should support further development to achieve tangible results
Searched and edited Sitthichot Supawan
source
https://www.chula.ac.th/highlight/56892/
https://ngthai.com/science/46397/ thai-maneedeang/
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