Protein WASF3 and Its Link to Chronic Fatigue Syndrome & Long-lasting COVID: A Breakthrough Discovery

2023-08-28 01:50:46

In an article published in the journal PNASresearchers from Maryland report that they have identified a protein called WASF3 whose levels are said to be abnormally high in the muscles of people suffering from chronic fatigue syndrome, now called myalgic encephalomyelitis.

In large quantities, this protein would harm the functioning of the mitochondria, the structures producing the energy necessary for the functioning of the cell. This might explain some symptoms reported by people affected by this disease, such as extreme exhaustion and a feeling of brain fog.

According to the study authors, an increase in WASF3 levels might be triggered if the endoplasmic reticulum — a cellular structure involved in protein production — experiences stress, as it does during infection with a virus. . The disease is often triggered following a viral infection.

This discovery might also be relevant in the treatment of long-lasting COVID, adds an expert quoted in the review Science. Indeed, the two diseases have extremely similar symptoms.

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