2024-09-27 13:00:12
During the fantastic Paris 2024 Olympic and Paralympic Games, many doctors took advantage of the French enthusiasm for sport to talk about its benefits on physical and mental health. But few have discussed the crucial role of physical activity in preventing Alzheimer’s disease.
However, Alzheimer’s disease – a neurodegenerative disease which affects 1 million patients in France and millions of people around the world – represents a colossal challenge for public health in developed countries. With the increase in life expectancy, this disease affects more and more people, thus raising the essential question of prevention. A question that is all the more burning as we do not yet have effective treatments without serious side effects.
As a reminder, the European health authorities (European Committee for Medicinal Products for Human Use, CMHP) did not authorize the placing of Leqembi on the European market this summer. This product, registered in the United States, China, Hong Kong, Israel, Japan, Great Britain and South Korea, is indisputably effective in reducing amyloid plaques, but the CMHP considered that the clinical benefit observed was not sufficient to justify the risks of treatment-related complications.
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In any case, if preventive action is possible, it should in no case be neglected. However, one of the most promising avenues of prevention for delaying the onset of this disease is physical activity.
But what really is the role of sport in preventing Alzheimer’s disease?
The challenge of Alzheimer’s disease
In France, 1 million people are affectedand this number continues to grow. These alarming figures underline the urgency of finding solutions to prevent or slow the progression of this disease.
Research on Alzheimer’s has made considerable progress in recent decades, but its mechanism is complex and still imperfectly understood. Only 1% of cases of Alzheimer’s disease are hereditary. Alzheimer’s disease is a multifactorial disease in which certain risk factors are modifiable and play an essential role in its appearance and development. According to the researchers40% of cases of Alzheimer’s disease could be avoided with appropriate prevention. And among the modifiable risk factors on which we can act, a sedentary lifestyle occupies an important place.
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