Pill against alopecia would recover 80% of hair in half a year

This condition affects men, women, and children, and can cause anxiety and depression.

An American pharmaceutical company announced that developed a drug that might cure alopecia areata: It would be a pill that, if taken twice a day, might recover 80% of fallen hair in six months.

The company Concert Pharmaceuticals announced on May 23 your test results THRIVE-AA1in which doses of the drug were administered CTP-543 a volunteers with alopecia.

The requirement to participate was have at least 50% hair loss (100 being the total loss). To conduct the study they gave 8mg of CTP-453 twice a day to one group, 12 milligrams twice a day to the second team and a third control team.

41.5% of patients who received 12 milligrams achieved 80% or more scalp hair coverage. Meanwhile, 29.6% of the group that received 8 milligrams achieved the same results.

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The pharmaceutical company will publish the results of a new trial in volunteers. With these results, they hope to submit a New Drug Application (NDA) in the first half of 2023 to the Food and Drug Administration (FDA), which might approve its sale and consumption.

How does CTP-543 work?

The drug inhibits enzymes Janus Kinaseknown as JAK1 y JAK2 (growth hormone), which are activated during an immune response.

When many JAKs are present, the inflammatory immune response causes hair loss.

According to scientific research, if the enzymes are inhibited, the effects of alopecia might be reversed.

What is alopecia areata?

Alopecia areata is a disease in which the immune system attacks healthy hair follicles.. According to information from Medlineplus, this type of alopecia may have genetic permanence. This autoimmune condition affects men, women and children

Recently the disease has been in the focus of world attention following the coup that Will Smith the god a Chris Rock during the award ceremony 2022 Oscars. At the event, Rock made fun of the alopecia he has Jada Pinkett Smithwife of the Oscar winner.

In the United States alone, it affects 6.8 million people. According to National Alopecia Foundation, the condition can lead to depression and anxiety.

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