It seems that “luck” has a role even in some disease cases, as geneticists have revealed why some infected people survive with obesity They are in relatively good health, while others suffer from life-changing illnesses such as type 2 diabetes and heart disease.
Although all obese people have a few or a lot of kilograms in common, two people can have the same BMI, but with very different amounts of fat.
The fat stored under the skin is less harmful than the fat stored around the organs such as the liver and heart, and the genes we are born with determine how and where this fat is stored, according to the Science Daily website.
lucky genes
While Dr Haniyeh Yagoutkar, a lecturer in biosciences at Brunel University London who led the research, explained that “some people have the unlucky fat genes, which means they store higher levels of fat everywhere, including under the skin, liver and pancreas.”
She pointed out that “this is linked to a higher risk of diseases such as type 2 diabetes,” noting that “some are more fortunate, as they have genes that lead to high subcutaneous fat only, while it is low in the liver.”
expressive (Shutterstock)
Using a technique known as Mendelian randomisation, the team of researchers found that, of the 37 diseases tested, 12, including coronary artery disease, stroke and diabetes, were directly linked to genes that determine whether or not a person had “favorable obesity.” ‘favourable adiposity.’
While it can be argued that nine diseases unrelated to obesity were most likely the result of carrying a lot of weight, such as a deep vein thrombosis or an arthritic knee.
Obesity risk
However, the researchers cautioned that regardless of whether a person has favorable or unfavorable obesity, obesity poses a risk to a person’s health, noting that even those with favorable obesity are still at increased risk of developing diseases such as gallstones and asthma when Adults and psoriasis.
They also found that some other diseases previously thought to be linked to a person’s weight turned out to be unrelated, such as Alzheimer’s disease.
expressive (Shutterstock)
What’s more, they said, the findings will help doctors decide whether to target the negative effects of someone’s obesity, or try to get them to shed just a few kilos.
Professor Timothy Frayling, Professor of Human Genetics at the University of Exeter, explained that there are many treatments that can lower high levels of fats in the blood and around the organs that do not affect the extra weight a person carries.
