2024-05-03 11:03:45
This article was commissioned by NUTRILITE and produced by Pan Science Planning.
What is the absorption rate of nutritional supplements?
Medications and nutritional supplements seem to play an increasingly important role in our lives every day. But have you ever thought that all these key molecules might not be absorbed by the human body? So what to do? The answer may lie in the absorption rate! Let’s discover this mystery together!
Can the nutrients you eat be absorbed effectively? picture/envato
When we swallow a capsule, this little pill begins an amazing journey. It enters the digestive tract through the mouth, mixes with gastric juices, is then pushed into the small intestine and is finally absorbed from the intestine into the bloodstream. This process seems simple, but it is actually fraught with pitfalls.
First, the challenge we face is that of drug solubility. Some ingredients are difficult to dissolve in water, meaning they may not be absorbed effectively once they enter the body. Especially for fat-soluble ingredients, they need to be absorbed through oil intervention, and this process is relatively complicated and the absorption rate is also low.
Have you ever heard of the “drug delivery system”?
To solve this problem, scientists have developed many drug delivery systems, the most notable of which areSelf-Emulsifying Drug Delivery System(Self-Emulsifying Drug Delivery Systems, referred to as SEDDS), also known as absorption enhancement technology. The core concept of this technology is to use oils, surfactants and auxiliary surfactants in the delivery system to form fine chylomicrons as soon as drugs and nutritional supplements enter the intestine, thereby improving the absorption rate medication.
Self-emulsifying drug delivery system, also known as absorption enhancement technology. picture/envato
Another point is that these fat-soluble drugs treated with SEDDS technology will be absorbed by the lymphatic system of the intestine following forming chylomicrons in the intestine. They can therefore bypass the first transit effect of the liver, reduce losses and retain more. at the same time medicinal activity. This allows drugs that would otherwise be difficult to absorb, such as the antiretroviral drug Ritonavir, used in treatments for HIV or COVID-19, and Nifedipine, which relieves angina, to work more effectively.
In addition to its application in pharmacotherapy, SEDDS technology is also widely used in the field of nutritional supplements. Many fat-soluble nutrients, such as vitamins A, D, E, K and EPA and DHA contained in fish oil, can improve their absorption efficiency through SEDDS technology to better meet the body’s nutritional needs .
With the advancement of science and technology, drugs can break through the limits and exert greater effectiveness, which is equivalent to a higher CP value. The emergence of SEDDS technology is one of the solutions to increase the absorption rate of drugs and nutritional supplements. In the future, with the continuous advancement of science and technology, it is believed that more drug delivery systems (DDS) will be launched to bring more benefits to human health.
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