Opening “Innovative Diabetes Medicine” in Thailand

According to the IDF Diabetes Atlas, there are 537 million people living with diabetes worldwide. More than 90% of them have type 2 diabetes, and nearly half are undiagnosed. It is expected that by 2030 this will increase to 643 million and by 2045 it will increase to 783 million.

While the diabetes situation in Thailand Data from public health statistics reports Ministry of Public Health Thailand has found that the incidence of diabetes tends to continually increase. In 2023, there will be 300,000 new patients per year. In 2022, there will be 3.3 million people with diabetes, an increase from 2012. In 2021, up to 150,000 people for screening new patients in 2023 found that screening for diabetes patients in people aged 35 years and over has not been screened.Diabetesup to 5 million people from a nationwide target of 22 million people

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Current guidelines for treating diabetes

Clinical Prof. Dr. Chaichan Deerojanawong, President of the Endocrine Society of Thailand Revealed that diabetes has always been an important problem for Thai people. Especially in an era where people’s lives have become more convenient. As a result, there are an increasing number of people with diabetes every year.

DiabetesIt is caused by abnormalities in the body’s ability to transport glucose into cells due to insulin deficiency and/or insulin resistance. As a result, blood sugar levels rise. Controlling blood sugar levels close to normal inpatientDiabetes is important in reducing the risk of complications. Diabetes includes kidney failure, blindness, and cardiovascular disease.

There are many ways to care for diabetes today, including diet control. exercise and use of drugs to reduce blood sugar levels These methods are important in helping to control blood sugar levels within normal limits. But at the same time, adjustments must be made to suit each patient individually because patients have different blood sugar levels and co-factors. Nowadays there are new medicines. That can be an option for effective diabetes care.

Innovative medicine for treating diabetes

During the initial period of treatmentDiabetesInsulin injections and sulfonylurea tablets are used to lower blood sugar levels. The main disadvantage of the above two groups of drugs is the occurrence of hypoglycemia and weight gain after treatment. In addition, there is metformin tablets, which do not cause hypoglycemia and weight gain. climb Nowadays, there are new innovative medicines. that is continuously developed in the treatment of diabetes Especially in the group that is an oral medicine. This is an option for patients who are not comfortable using injection methods, including:

1. GLP-1 Receptor Agonists

GLP-1 Receptor Agonists work by stimulating the GLP-1 receptor, which is the same hormone that is produced in the intestines in the body. Makes blood sugar levels decrease The medicine only works when there is high blood sugar. Therefore, it will not increase the risk of hypoglycemia in the blood. In addition, it can also help in weight loss, which is an important advantage for diabetic patients who often have problems with being overweight.

This group of drugs is also useful in reducing the risk of cardiovascular disease. Therefore, this is a feature that makes GLP-1 Receptor Agonists an attractive alternative. This is especially true for patients at high risk of cardiovascular disease. In addition, recent data has shown that it can slow down kidney deterioration in diabetic patients as well.

Recently, GLP-1 Receptor Agonists have evolved from their original form. which is an injection and comes as an oral drug that has similar efficacy This is a breakthrough that represents a new innovation that gives patients more convenient treatment options.

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2. SGLT2 Inhibitors

SGLT2 Inhibitors play a role in controlling blood sugar levels. By inhibiting the reabsorption of sugar by the kidneys. Causes the body to excrete sugar with urine. This group of drugs does not cause hypoglycemia and has the advantage of reducing the risk of heart disease and slowing down the deterioration of the kidneys. It is considered another option for treating diabetes.

3. DPP-4 Inhibitors

DPP-4 Inhibitors work by blocking the DPP-4 enzyme, which is the enzyme that breaks down the hormone GLP-1 in the body. DPP-4 Inhibitors have the advantage of not increasing the risk of hypoglycemia. But this group of drugs has no effect on body weight and has no direct effect on reducing the risk of heart disease and kidney disease.

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Research progress in Thailand

Clinical research is extremely important to doctors andpatient Especially in the context of Thailand Clinical research that is specific to the Thai population It not only helps to understand needs and problems.healthof patients but can also develop more appropriate and effective treatment guidelines

innovationdiabetes medicinein Thailand at present It has affected patient care by increasing treatment options that suit individual needs. This is considered an important advancement that should be supported and developed continuously. But these are the only good developments. Probably not enough to prevent diabetes.

Controlling your diet and exercising regularly It remains the main strategy for effective prevention and treatment of diabetes. Understanding the consumption of types and quantities of food Changing lifestyle habits will also help reduce the risk of diabetes complications.

however innovationNew medicines for treating diabetes and consuming the right food along with regular exercise Therefore, it is the key to helping manage diabetes in Thailand.

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