2024-08-15 06:00:05
Could such a harmless pill be changing our health prospects? Recent research provides some insight. The results of this study could transform our understanding of a major health risk.
Mass General Brigham researchers reveal surprising data on the preventive impact of aspirin on colorectal cancer.
Researchers followed men and women for more than 30 years. Those with unhealthy lifestyles, characterized by poor diet, lack of exercise, excessive alcohol consumption and smoking, benefited most from theusage regular aspirin, according to the study led by Mass General Brigham.
According to the study published in JAMA Oncologyaspirin may reduce the risk of colorectal cancer in people with lifestyle risk factors. Andrew Chan, co-author of the study, emphasizes the importance of a prevention personalized, especially for people at high risk.
The study was based on health data from 107,655 participants. The results showed a 10-year cumulative incidence of colorectal cancer of 1.98% among regular aspirin users, compared with 2.95% among those who did not take aspirin. Aspirin appeared to be particularly beneficial for participants with unhealthy lifestyles.
Participants with the lowest lifestyle scores saw their risk of colorectal cancer reduced from 3.4% to 2.12% with aspirin. In contrast, those with the highest scores saw only a marginal reduction. It is estimated that treating 78 patients with aspirin would prevent one case of colorectal cancer over a 10-year period for the least healthy group.
Aspirin, by blocking pro-inflammatory proteins and influencing immune responses, may prevent colorectal cancer through various mechanisms. However, the study did not address potential side effects such as bleeding.
The results of this study, although encouraging, require further evaluation to confirm the benefits of aspirin in different population groups.
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