Those who survived every wave of coronavirus infection in the past month Scientists have found that the person may have a special mutation gene. that have been exposed to germs never been infected with such disease. But virus experts say the latest research suggests it may be due to some genes. The one who came to help more would be… Superdodger.
Dr. Anan Chongkaewwatana, virologist Director of Animal Health Innovation Research and Management Group, Center for Genetic Engineering and National Biotechnology (Biotech) NSTDA posted via Facebook Anan Jongkaewwattana on October 1, 2022 stating that
The most obvious Superdodger is probably the case of People who have been exposed to HIV but have never been infected with the virus. which is a phenomenon very famous in the past until it was discovered It’s important to note that HIV doesn’t just bind to CD4 on white blood cells. can get infected There’s another protein called CCR5 that opens the door. Superdodger in the study was a person with a key mutation on the CCR5-protein gene, causing this protein to enter the cell. no expression On white blood cells, HIV can only bind to CD4, but no help. to be attached to the cell. It is considered a very important body of knowledge that makes people try to get ideas human gene modification to have no expression of CCR5 in order to treat infections or AIDS patients that used to be very popular in the industry (https://www.nejm.org/doi/full/10.1056/NEJMoa0802905)
But the COVID Superdodger will be harder than the case of HIV. because we know Viruses use the ACE2 receptor protein to enter cells. It would be very difficult for someone to have a mutation, as is the case with HIV, because ACE2 has many important functions. especially the control The body’s blood pressure system, simply put, we lack ACE2 on cells like we can’t lack CCR5 on the cell surface. So the true definition of COVID Superdodger would be that someone who has “never been infected” probably isn’t, but it might be. already infected never had more symptoms
The latest research that comes out as a preprint seems to say that people who are Superdodgers in the context of Covid. may be related to a gene called HLA which this protein play an important role in control immune system to be ready to fight the virus Without prior stimulation, some people may also have previously stimulated HLA. Other coronavirus infections from the common cold in the past then can come across Prevents infection with the SARS-CoV-2 strain of corona without the need for time to stimulate like normal people, which the virus does not have time to multiply. until showing symptoms in those people
https://www.medrxiv.org/content/10.1101/2021.05.13.21257065v2
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Reference and thanks for information from:
Facebook : Anan Jongkaewwattana (Dr. Anan Jongkaewwattana)
https://www.facebook.com/anan.jongkaewwattana