2023-10-16 01:23:00
Health Copenhagen, Denmark16 Oct. ’23 8:23
New research presented today at UEG Week 2023 found a significant association between birth weight and the development of non-alcoholic fatty liver disease. which is currently known as Metabolic fatty liver disease (MASLD) in young adults.
especially Babies with low birth weight You are four times more likely to develop MASLD in childhood, adolescence, or adulthood.
Researchers conducted a controlled study of people aged 25 years and younger. A total of 165 people were diagnosed with MASLD between January 1992 and April 2017. Each person with MASLD was matched with up to five controls from the general population who were similar in terms of age. Gender, calendar year, and area of residence
People born with a low birth weight (less than 2,500 grams, or 5 pounds, 8 ounces) are four times more likely to develop MASLD than those born with a normal birth weight. Those born with a lower birth weight Those below the 10th percentile for gestational age (SGA) were also three times more likely to develop early MASLD compared to those with normal birth weight. (10th-90th percentile)
In addition, researchers found that People with low birth weight or underweight for gestational age There is a ~6 times higher risk of developing severe MASLD in the form of liver fibrosis and cirrhosis.
Dr. Fahim Ebrahimi, main author Express your opinion that “Although previous research has shown a link between low birth weight and major diseases, But the connection to MASLD is unclear. Our research presents compelling evidence that factors related to fetal development significantly impact the development of MASLD and progressive liver disease.”
As obesity rates increase, MASLD has become the most common cause of chronic liver disease worldwide. In Europe alone it is estimated to affect more than 25% of adults, and its prevalence is increasing.
Dr Ebrahimi added: “It is of great concern that people with low birth weight may be at increased risk of developing the disease at a young age, as MASLD tends to have an early onset. Continues into adulthood And with an increased risk of cirrhosis and end-stage liver disease, it is important that we develop effective, proactive strategies to identify those at risk and help reduce the burden of this disease.”
For further information or to request an interview, please contact [email protected].
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