2024-02-10 14:00:00
For this research, scientists focused on studying fibroblasts, which are the cells responsible for producing connective tissue.
Photo: Archive
A group of researchers found the two types of cells in the penis that play a fundamental role in generating and maintaining an erection. This was the finding of a study carried out on mice and described in the journal Science. (Read: They report a shortage of misoprostol, but Profamilia says it has units available)
Professor Ji-Kan Ryu, a researcher at Inha University School of Medicine and author of the study, explained that these results may be important for understanding erectile dysfunction in older men. It is because “the mechanisms of penile erection are similar in mice and humans.”
For this research, scientists focused on studying fibroblasts, which are the cells responsible for producing connective tissue and which are the most abundant in the corpora cavernosa, which are the columns of spongy tissue that cross the shaft of the penis.
In the case of the mice, which were genetically modified, the scientists identified two groups of fibroblasts that are next to the blood vessels in the corpora cavernosa. In this case, they altered the activity of these fibroblasts and thus might understand how changes occurred in blood flow to the penis. (You can read: Brazil’s concern regarding the increase in dengue cases: there will be more than 140,000 in 2024)
Tests revealed that these cells are responsible for triggering erections and they do so by absorbing a hormone that keeps the penis flaccid. It is norepinephrine. “When this is stored, the cells help the relevant blood vessels dilate,” they report in the document.
They also found that the ability of these cells to perform this function might change according to the concentration in the penile tissue. For example, the more fibroblasts there are, the more solid the result will be.
“Compared to young mice, old mice had fewer fibroblasts. “Which suggests that aging may contribute to erectile dysfunction by reducing the number of these cells over time,” the researchers clarified.
Likewise, they found that there was a molecular switch within fibroblasts, which is known as the “Notch signaling pathway.” “Activating these switches in fibroblasts might open new therapeutic alternatives for the treatment of erectile dysfunction,” they added.
Currently, Viagra is the most common medication to treat erectile dysfunction. However, it only works in up to 30% of patients and cannot be used by people who use certain types of medicines or who have a specific medical condition. (You may be interested: They want cigarettes to disappear from Instagram, Netflix and Facebook)
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