Dr. Anan Chongkaewwatana, virologist Director of Animal Health and Management Innovation Research Group National Center for Genetic Engineering and Biotechnology (Bio-Tech), National Science and Technology Development Agency (NSTDA) posted on Facebook regarding the case of people who “Never contracted covid” can survive every season, every round, with the past news and the article states that people “Never contracted covid” maybe Super Dodgers (Superd Dodger) and is preferred by scientists. Regarding the matter, Dr. Anan explained as follows:
Dr. Anan stated that those who “Never contracted covid” with the word Super Dodgers The most obvious would be the case of people who have been exposed to HIV but have never been infected with the virus. which was a very famous phenomenon in the past Until it was discovered that HIV not only binds to CD4 on white blood cells, it can infect. There is another protein called CCR5, which opens the door for the virus to enter cells. Superdodger in the study was that people with a key mutation on the CCR5-producing gene caused the protein to not be expressed on the white blood cells at all, thus HIV. but binds to CD4, but does not have a helper to attach to the cell
Dr. Anan stated that it is a very important body of knowledge. that has led people to try to come up with the idea of modifying the human gene to suppress CCR5 expression as a treatment for infection; or AIDS patients That used to be very popular news in the industry.
but Super Dodgers The case of COVID is more difficult than the case of HIV because we know that the virus uses the ACE2 receptor protein to enter cells. It would be very difficult for someone to have a mutation, as is the case with HIV, because ACE2 has many important functions. In particular, the control of the body’s blood pressure system. In other words, we lack ACE2 on the cells like we cannot lack CCR5 on the cell surface. Super Dodgers of covids. Really use that people who “Never contracted covid” Probably not, but probably someone who has been infected and has never had more symptoms.
The latest research that comes out as a preprint seems to say that people who are Super Dodgers In the context of COVID It may be related to a gene called HLA. This protein plays a key role in regulating the body’s immune system to fight off the virus without activation. Some people may have HLA that was previously triggered by other coronaviruses. from the common cold in the past Then can come across to prevent infection with the SARS-CoV-2 strain of corona without the need for stimulation time like normal people. The virus does not have time to multiply until symptoms appear in those people.
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