On August 20, 65, Dr. Yong Phu Worawan, the head of the Center specializes in clinical virology. Department of Pediatrics Faculty of Medicine Chulalongkorn University Posted a message via Facebook, Yong Poovorawan stated that…
HFMD hand, foot and mouth disease vaccine
20 August 2022
after school The outbreak of hand, foot and mouth disease is evident.
hand-foot-mouth syndrome It can be caused by many viruses such as Coxsackie A, such as CA6, CA16 CB, Enterovirus A and many others.
The most severe case with a chance of developing encephalitis is EV-A 71. are more young children than older children The younger the age, the more likely it is to be born. getting older
In this year’s outbreak, most of the CA6 strains show considerable skin symptoms. There are blisters on the roof of the mouth, hands, feet, elbows, knees, around the buttocks, and when healed, some will have marks on the nails.
In the outbreak, some years will be caused by the EV71 strain, as shown in the picture, which had been epidemic in 2017 or 5 years ago. Our center has been monitoring the hand-foot-mouth disease outbreak for more than 10 years until now. as shown in the graph to see each year what is the species for the benefit of care and protection
Hand-foot-mouth protection vaccine that is said to be incorrect. It must be called a vaccine against EV71 only because it cannot be crossed to prevent CA or CB. There will be no need to prevent hand, foot and mouth this year. Most of them are CA6.
The vaccine against EV71 is made from the EV71 subspecies C4 strain, but our 2017 outbreak in Thailand was of the B5 strain and before the covid outbreak we found that the EV71 that was found was starting to be a C strain! And then it stopped, and this year most of the outbreaks detected so far were not EV71, but CA6.
No clinical studies have been conducted. to confirm how effective crossbreeding is. Only in vitro studies have been performed. The mainland China vaccine is made from the C4 strain, the Taiwanese vaccine studied. Made from the B4 strain.
What must be understood is The hand-foot-mouth vaccine EV71 does not protect against Hand-foot-mouth that occurs mostly in Thailand. with strains CA6, CA16, etc. will be specific protection against EV71 and what will need to be studied cross-species protection between EV71 C4 to protect against EV71 B5 or C1 strains found in our home how much It is something that should be planned for further studies. to consider the future use of the vaccine
