2023-10-05 20:00:07
Molnupiravir is said to trigger corona mutations. Pharmacologist Markus Zeitlinger explains in the “Today” interview.
Until now, the antiviral drug molnupiravir was considered a proven remedy once morest Covid-19. But now one is published in the specialist journal “Nature” Published study suggests that it might contribute to the emergence of new corona variants.
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“It should be noted that the drug was not specifically manufactured for use once morest Covid-19, but was purely a flu drug, which was never approved for this,” explains Markus Zeitlinger, clinical pharmacologist at the Med-Uni Vienna in the “Today”-Conversation. Due to the desperate Corona situation, it was taken out of the medication drawer and used before the official approval process was completed – with the approval of the European Medicines Agency (EMA). “The submission process and deployment to sick people overlapped.”
Mutated viruses passed on
Through the use of molnupiravir in sick people, it was discovered that the drug causes mutations in its genome when the virus replicates. Since this is harmful to the virus, it is intended to stop replication and massively reduce the viral load in the body within 24 hours. “The immune system should be able to do the rest,” said the expert.
“This did not create a supervirus.”
However, this only works if the immune system works strong enough. However, if a person’s immune response is weak and pre-stressed, mutated viruses may survive and ultimately be passed on. “Basically, a mutation is usually found in people who have taken this medication,” explains Zeitlinger. There were also transmissions, but nothing more. “This did not create a supervirus.”
And now?
On February 24, 2023, the European Medicines Agency (EMA) announced that it would refuse to approve molnupiravir in the EU. “You should learn from it,” emphasizes Zeitlinger. Another Study also found that the use of this drug did not reduce the frequency of hospitalizations or deaths among high-risk patients. The developer Merck has now withdrawn the drug.
Nav-Account red Time05.10.2023, 22:00| Akt: 05.10.2023, 22:00
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