Ms. Lin, who is in her 50s, has been in the clinic for a long time due to chronic fatigue. The doctor found that her liver index was too high, which was suspected to be caused by metabolic steatohepatitis. She continued to take traditional liver-protecting drugs, but the effect was limited. Later, she was referred to Annan Hospital Gastroenterology treatment. After blood and liver biopsy, the diagnosis was metabolic steatohepatitis. After one month of drug treatment, Ms. Lin successfully lost 5 kg, her liver index returned to normal, and her fatigue symptoms were also relieved.
Metabolic fatty liver disease has no obvious symptoms and is difficult to alert
According to Cai Kunfeng, director of the Department of Gastroenterology at Annan Hospital, many people have excessive caloric intake in their eating habits, coupled with lack of exercise, high stress in work and life, and irregular work and rest, the number of patients with metabolic fatty liver is increasing, of which 8 Overweight patients with overweight or even have metabolic fatty liver disease. These patients often have no obvious clinical symptoms, so they are not alert. In the long run, metabolic fatty liver disease may evolve into hepatitis, and in severe cases, it may even progress to liver fibrosis and hepatic fibrosis. cirrhosis of the liver.
Director Cai Kunfeng explained that according to statistics, about 5% of patients with metabolic fatty liver will eventually develop cirrhosis, and the insulin resistance and chronic inflammation of the liver caused by obesity release inflammatory substances, which are considered to be the cause of metabolic fatty liver disease. The etiology, abdominal ultrasound and blood biochemical examinations help patients to detect health conditions early, and physicians can intervene in treatment, and the most important thing in treatment is weight control.
Obesity accumulates liver fat higher than drinking alcohol
Director Cai himself is also a specialist physician of the Obesity Medicine Association. He pointed out that obesity has a greater impact on the accumulation of liver fat than drinking alcohol, and weight loss can improve the degree of metabolic steatohepatitis. Losing more than 9% of the body weight can effectively improve liver tissue, and even a small amount of weight loss can improve. Therefore, effective diet management and moderate exercise are the first steps of treatment; the drug part, commonly known as “slender needles”, the agonists of glucosinolate peptide-1 receptors can also reduce appetite, control weight, and others such as vitamins E, Stain or Niacin drugs have also been shown to be effective in small clinical studies.
Director Cai Kunfeng pointed out that according to the latest literature of the authoritative journal “Lancet”, most patients who received gastroscopic gastric shrinkage therapy can still maintain a 25% weight loss effect after 2 years of follow-up. For moderately obese patients, namely For those with BMI > 30, intragastric botulinum toxin injection can also be performed through a gastroscope to delay gastric emptying, and gastroscope gastroscopic therapy can be provided to reduce the patient’s gastric capacity and achieve weight loss control. The advantage of this treatment is that it is minimally invasive, and there is no wound on the body surface. Together with drug treatment and adjustment of dietary habits, it is the fundamental way to treat metabolic steatohepatitis.
◎ Image source/Provided by Dazhi Image/shutterstock
◎ Consultant / Dr. Cai Kunfeng
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